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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Álex Díaz# | 1.278 | 1980-1991 | |
| 2 | Yukinaga Takahashi# | 1.367 | 1979-1990 | |
| 3 | Gerry Colenutt# | 1.467 | 1985-1991 | |
| 4 | Juan Barajas | 1.479 | 1965-1974 | |
| 5 | Cecil Everett | 1.504 | 1975-1987 | |
| 6 | Ángel Burgos | 1.528 | 1970-1975 | |
| 7 | Tom Baldwin | 1.558 | 1968-1974 | |
| 8 | Rex Lipinski* | 1.655 | 1948-1959 | |
| 9 | Colm Chantler | 1.688 | 1972-1973 | |
| 10 | António González | 1.761 | 1970-1974 | |
| 11 | Matthew Dibb | 1.800 | 1976-1983 | |
| 12 | José Fuentes | 1.880 | 1969-1984 | |
| 13 | Travis Brown | 1.929 | 1966-1976 | |
| 14 | Kojiro Miyazaki | 2.045 | 1971-1974 | |
| 15 | Wijnand Veenbrink | 2.160 | 1970-1972 | |
| 16 | Francisco Rivera | 2.170 | 1970-1985 | |
| 17 | Enrico Álvarez | 2.204 | 1952-1963 | |
| 18 | Jonathan Laybolt | 2.250 | 1970-1977 | |
| 19 | Jérémy Delamare | 2.265 | 1970-1983 | |
| 20 | José Palma# | 2.267 | 1975-1988 | |
| 21 | Albert Dillon | 2.271 | 1979-1988 | |
| 21 | Dermot Hollis# | 2.271 | 1988-1991 | |
| 23 | Chao Men# | 2.287 | 1983-1991 | |
| 24 | Elliott Mathews | 2.290 | 1972-1983 | |
| 25 | Bill Drover | 2.298 | 1959-1970 | |
| 26 | Peter Long | 2.305 | 1979-1985 | |
| 27 | Bilal bin Harun# | 2.309 | 1982-1990 | |
| 28 | Arnie Mahoney# | 2.365 | 1982-1988 | |
| 29 | Brian Howard* | 2.380 | 1937-1954 | |
| 30 | Naomichi Ine | 2.406 | 1968-1972 | |
| 31 | Bruce Burke | 2.411 | 1926-1933 | |
| 32 | Michel Bel | 2.413 | 1957-1964 | |
| 33 | Everton Ullyatt# | 2.432 | 1988-1990 | |
| 34 | Jason Brown# | 2.455 | 1979-1991 | |
| 34 | John Cole# | 2.455 | 1984-1990 | |
| 34 | Francisco Rodríguez | 2.455 | 1923-1931 | |
| 37 | Roberto Márquez | 2.471 | 1911-1918 | |
| 38 | Anthony Moore | 2.480 | 1967-1981 | |
| 39 | Habimana Zuri | 2.495 | 1970-1979 | |
| 40 | Louis Dillon | 2.502 | 1970-1975 | |
| 41 | Ryan Tinker | 2.513 | 1971-1980 | |
| 42 | António Gonzáles | 2.517 | 1972-1980 | |
| 43 | Alemu Diallo | 2.520 | 1970-1980 | |
| 44 | Frazer Dalziel | 2.524 | 1972-1976 | |
| 45 | Kristian Røhne | 2.538 | 1970-1980 | |
| 46 | Abraham Washington# | 2.556 | 1984-1988 | |
| 47 | Carlton Lavington | 2.569 | 1969-1981 | |
| 48 | John López | 2.574 | 1974-1983 | |
| 49 | Armand Lucas | 2.581 | 1970-1977 | |
| 50 | John Fowler | 2.600 | 1923-1932 | |
| 51 | Aindreas McKillicane | 2.602 | 1974-1985 | |
| 52 | Laoghaire Ritchie* | 2.603 | 1964-1977 | |
| 53 | Peter Mrazek | 2.613 | 1957-1962 | |
| 53 | Bob Wheeler | 2.613 | 1911-1915 | |
| 55 | Luis Castillo | 2.617 | 1962-1975 | |
| 56 | Júlio Solíz | 2.618 | 1966-1977 | |
| 57 | Steve Ferguson# | 2.619 | 1981-1990 | |
| 58 | Rubén Pérez# | 2.621 | 1981-1991 | |
| 59 | Tyler Frisby# | 2.638 | 1981-1991 | |
| 60 | José Álvarez | 2.639 | 1970-1975 | |
| 61 | Sergio Vásquez | 2.642 | 1970-1986 | |
| 62 | Raúl Jiménez | 2.643 | 1967-1977 | |
| 63 | Marvin Smith | 2.647 | 1971-1985 | |
| 64 | Qaraja Badr al Din# | 2.656 | 1987-1989 | |
| 65 | Kyle Tyack# | 2.676 | 1979-1990 | |
| 66 | Javier Galván* | 2.677 | 1949-1959 | |
| 67 | Dale Haynes | 2.681 | 1911-1918 | |
| 68 | Andy Flowers* | 2.682 | 1962-1976 | |
| 69 | José Torres | 2.684 | 1975-1989 | |
| 70 | Louie Batt | 2.696 | 1967-1982 | |
| 71 | Pearson Tuxford* | 2.705 | 1939-1956 | |
| 72 | Callum Simpson | 2.749 | 1983-1990 | |
| 73 | Ambrose Sanders# | 2.753 | 1982-1991 | |
| 74 | Tomás León | 2.755 | 1926-1939 | |
| 74 | Kalijan Pewar | 2.755 | 1971-1981 | |
| 74 | Gilberto Ramírez# | 2.755 | 1982-1991 | |
| 74 | Tara Ringrose | 2.755 | 1974-1986 | |
| 78 | Manny López | 2.757 | 1969-1980 | |
| 79 | Barry Richard# | 2.764 | 1988-1991 | |
| 80 | Alex Lewis | 2.772 | 1974-1984 | |
| 81 | Carlos Ruíz | 2.782 | 1964-1973 | |
| 82 | Simon Schwer# | 2.784 | 1983-1989 | |
| 83 | Tom Smith | 2.786 | 1944-1951 | |
| 83 | Michael Tripp | 2.786 | 1955-1964 | |
| 85 | Ignacio Palácios | 2.793 | 1961-1974 | |
| 85 | Walt West | 2.793 | 1970-1978 | |
| 87 | Marty Hensley* | 2.795 | 1957-1973 | |
| 88 | Robbie MacClacher | 2.798 | 1970-1978 | |
| 89 | Darby Sherman | 2.802 | 1939-1951 | |
| 90 | Júlio Contreras | 2.807 | 1930-1942 | |
| 91 | Jaakko Salomäki | 2.829 | 1970-1973 | |
| 91 | Craig Taylor* | 2.829 | 1921-1925 | |
| 93 | Graham Lee | 2.830 | 1972-1979 | |
| 94 | Finley Fletcher | 2.831 | 1972-1977 | |
| 94 | António González | 2.831 | 1926-1929 | |
| 96 | Joe Todd# | 2.833 | 1984-1991 | |
| 97 | Michael Steward | 2.834 | 1972-1979 | |
| 98 | Terho Forsbacka# | 2.842 | 1982-1991 | |
| 98 | Brett Riley | 2.842 | 1911-1918 | |
| 98 | Luis Torres | 2.842 | 1924-1936 |
