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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Raúl Cruz | 97 | 1978-1989 | |
| 2 | Jimmy Washington | 85 | 1949-1960 | |
| 3 | Claudio Zamora | 79 | 1961-1967 | |
| 4 | Samuel Gaze# | 64 | 1988-1991 | |
| 4 | Max Hill | 64 | 1914-1921 | |
| 6 | Román Vásquez | 63 | 1945-1954 | |
| 7 | Ismael Ramírez | 53 | 1963-1970 | |
| 8 | Lawrence Hudson | 51 | 1956-1962 | |
| 9 | Pancho Martínez | 49 | 1911-1911 | |
| 9 | Víctor Padilla | 49 | 1914-1918 | |
| 9 | Noam Peltier | 49 | 1974-1983 | |
| 9 | Nate Wise | 49 | 1913-1919 | |
| 13 | Francisco Lozano | 47 | 1911-1914 | |
| 14 | Stan Adams | 44 | 1911-1915 | |
| 15 | Santiago Mejía | 43 | 1978-1988 | |
| 15 | Ken Woods | 43 | 1976-1990 | |
| 17 | Mark Burrows | 42 | 1912-1917 | |
| 18 | Juan Pérez | 41 | 1948-1955 | |
| 19 | Jesús García | 40 | 1913-1921 | |
| 20 | Aaron Maryadi | 39 | 1937-1946 | |
| 21 | Bill Gross | 38 | 1974-1987 | |
| 21 | António Guerra | 38 | 1962-1971 | |
| 21 | Don Harper | 38 | 1967-1971 | |
| 21 | Ed Reed | 38 | 1911-1916 | |
| 25 | Armando Crespo | 37 | 1950-1954 | |
| 25 | Juan Elías# | 37 | 1982-1988 | |
| 25 | Milo MacPherson# | 37 | 1984-1988 | |
| 25 | Justin Sargent | 37 | 1914-1919 | |
| 29 | Larry Carey | 36 | 1946-1958 | |
| 29 | Pancho Marrero | 36 | 1916-1925 | |
| 29 | Jerry Milligan | 36 | 1953-1960 | |
| 29 | Terry Vanderven | 36 | 1946-1955 | |
| 33 | Bob Hawkins | 35 | 1935-1946 | |
| 33 | Armando Reyes | 35 | 1916-1926 | |
| 33 | Cris Rivas# | 35 | 1989-1990 | |
| 33 | Lee Wilson | 35 | 1913-1917 | |
| 37 | Matin bin Butrus | 34 | 1970-1978 | |
| 37 | James Davis | 34 | 1949-1952 | |
| 37 | Félix Méndez | 34 | 1961-1968 | |
| 40 | Phillip Cameron | 33 | 1946-1952 | |
| 40 | Walton Harris | 33 | 1912-1914 | |
| 40 | Todd Miller | 33 | 1928-1933 | |
| 40 | Júlio Pacheco | 33 | 1929-1940 | |
| 44 | Alberto Martínez | 32 | 1983-1989 | |
| 45 | Clarence Dean | 30 | 1984-1987 | |
| 45 | Roberto Macías | 30 | 1937-1945 | |
| 47 | Randy de Lange | 29 | 1983-1989 | |
| 47 | António Rosário | 29 | 1915-1921 | |
| 49 | Francisco Gutiérrez | 28 | 1950-1958 | |
| 49 | Dennis Lewis | 28 | 1962-1969 | |
| 49 | Paul Lewis# | 28 | 1978-1984 | |
| 49 | Trevor Stone | 28 | 1930-1937 | |
| 53 | Germán García | 27 | 1971-1976 | |
| 53 | Nick Howard | 27 | 1968-1969 | |
| 53 | António Martínez | 27 | 1944-1950 | |
| 53 | Walter McPherson | 27 | 1937-1946 | |
| 53 | Gideon Vellenoweth | 27 | 1942-1949 | |
| 58 | Blake Andrews | 26 | 1927-1932 | |
| 58 | Mike Gladstone | 26 | 1916-1917 | |
| 58 | Duane Lee | 26 | 1911-1912 | |
| 58 | Matt Martin | 26 | 1912-1918 | |
| 58 | Steve Matthews | 26 | 1911-1911 | |
| 63 | Carlos De La Cruz | 25 | 1975-1982 | |
| 63 | Larry McCarthy | 25 | 1924-1928 | |
| 63 | Esteban Ramos | 25 | 1942-1949 | |
| 63 | José Reyes | 25 | 1956-1966 | |
| 67 | Bob Anderson | 24 | 1977-1987 | |
| 67 | Steve Lee | 24 | 1955-1958 | |
| 67 | Jeff McDaniel# | 24 | 1983-1991 | |
| 67 | Luis Mota# | 24 | 1985-1989 | |
| 71 | Emílio Alvarado | 23 | 1913-1924 | |
| 71 | Mus'ad bin Bursuq | 23 | 1975-1976 | |
| 71 | Matt Brown | 23 | 1911-1914 | |
| 71 | Chris Mathews | 23 | 1917-1923 | |
| 71 | Ronnie Moore | 23 | 1952-1955 | |
| 76 | Manuel Castro | 22 | 1912-1912 | |
| 76 | Gérard Martin | 22 | 1944-1947 | |
| 76 | John Taylor | 22 | 1927-1932 | |
| 76 | Pat Watson | 22 | 1911-1916 | |
| 80 | Miguel Díaz | 21 | 1958-1960 | |
| 80 | Casey Dickson | 21 | 1911-1913 | |
| 80 | José Hernández | 21 | 1940-1952 | |
| 80 | Rafael Martínez* | 21 | 1924-1926 | |
| 80 | Mark Nelson | 21 | 1975-1989 | |
| 80 | Greg Pérez | 21 | 1981-1984 | |
| 80 | Ramón Salinas | 21 | 1952-1960 | |
| 80 | Mark Todd | 21 | 1931-1945 | |
| 88 | Sergio Berrios | 20 | 1941-1943 | |
| 88 | David Booth | 20 | 1912-1915 | |
| 88 | Scott George | 20 | 1913-1916 | |
| 88 | Fred Lewis | 20 | 1915-1917 | |
| 88 | Makoto Okamoto# | 20 | 1982-1989 | |
| 88 | Remon Oude Nijhuis | 20 | 1950-1956 | |
| 88 | Jorge Ramírez | 20 | 1973-1978 | |
| 95 | Flint Andrews | 19 | 1942-1953 | |
| 95 | Freek Boermeester | 19 | 1947-1950 | |
| 95 | Charlie Butler | 19 | 1977-1988 | |
| 95 | Pedro Flores | 19 | 1944-1949 | |
| 95 | Raúl Navarro | 19 | 1920-1924 | |
| 95 | Joaquín Varela | 19 | 1972-1984 |
