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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | SO | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Roberto Macías | 472 | 1937-1945 | |
| 2 | Francisco Lozano | 412 | 1911-1914 | |
| 3 | Theodore Copeland | 352 | 1920-1931 | |
| 4 | Román Vásquez | 335 | 1945-1954 | |
| 5 | Rafael Martínez* | 299 | 1924-1926 | |
| 6 | Santiago Mejía | 291 | 1978-1988 | |
| 7 | José Hernández | 277 | 1940-1952 | |
| 8 | Jesús García | 274 | 1913-1921 | |
| 9 | Jimmy Washington | 272 | 1949-1960 | |
| 10 | Juan Pérez | 257 | 1948-1955 | |
| 11 | Larry Carey | 247 | 1946-1958 | |
| 12 | Ed Reed | 234 | 1911-1916 | |
| 13 | Walter McPherson | 228 | 1937-1946 | |
| 14 | Raúl Cruz | 227 | 1978-1989 | |
| 15 | Phillip Cameron | 221 | 1946-1952 | |
| 16 | John Bird | 215 | 1960-1964 | |
| 16 | António Prieto | 215 | 1933-1936 | |
| 16 | Esteban Ramos | 215 | 1942-1949 | |
| 19 | Lee Wilson | 210 | 1913-1917 | |
| 20 | Armando Reyes | 206 | 1916-1926 | |
| 21 | Samuel Gaze# | 204 | 1988-1991 | |
| 22 | Lawrence Hudson | 202 | 1956-1962 | |
| 23 | Carlos De La Cruz | 201 | 1975-1982 | |
| 24 | Claudio Zamora | 196 | 1961-1967 | |
| 25 | Norberto Estrada | 192 | 1954-1959 | |
| 25 | Pancho Marrero | 192 | 1916-1925 | |
| 25 | Steve Matthews | 192 | 1911-1911 | |
| 28 | Jeff McDaniel# | 185 | 1983-1991 | |
| 29 | Max Hill | 183 | 1914-1921 | |
| 30 | Kent Rodríguez Jr.# | 179 | 1986-1991 | |
| 31 | Ismael Ramírez | 176 | 1963-1970 | |
| 32 | Alberto Martínez | 174 | 1983-1989 | |
| 33 | Félix Méndez | 169 | 1961-1968 | |
| 34 | Johan Guildenstern | 161 | 1933-1939 | |
| 35 | Paul Lewis# | 160 | 1978-1984 | |
| 35 | Ed Reynolds | 160 | 1915-1921 | |
| 37 | Roosevelt Nelson | 158 | 1950-1953 | |
| 38 | Carlos Garza | 154 | 1923-1933 | |
| 39 | Ramón Salinas | 152 | 1952-1960 | |
| 40 | Bob Anderson | 151 | 1977-1987 | |
| 40 | Kevin McAleer | 151 | 1957-1964 | |
| 40 | Víctor Padilla | 151 | 1914-1918 | |
| 43 | Fernando Soto | 150 | 1924-1933 | |
| 44 | Clifford King | 149 | 1951-1955 | |
| 44 | José Reyes | 149 | 1956-1966 | |
| 46 | Nakazo Suzuki | 146 | 1932-1941 | |
| 47 | Larry McCarthy | 141 | 1924-1928 | |
| 48 | Ronnie Moore | 139 | 1952-1955 | |
| 49 | Brit Cornett | 138 | 1935-1941 | |
| 50 | António Rosário | 137 | 1915-1921 | |
| 51 | Emílio Alvarado | 135 | 1913-1924 | |
| 51 | Remon Oude Nijhuis | 135 | 1950-1956 | |
| 53 | Aaron Maryadi | 134 | 1937-1946 | |
| 53 | Mark Todd | 134 | 1931-1945 | |
| 55 | John Taylor | 133 | 1927-1932 | |
| 56 | Randy de Lange | 131 | 1983-1989 | |
| 56 | Linwood Flores | 131 | 1921-1936 | |
| 58 | Jerry Milligan | 130 | 1953-1960 | |
| 59 | Flint Andrews | 129 | 1942-1953 | |
| 59 | António Martínez | 129 | 1944-1950 | |
| 61 | Don Harper | 128 | 1967-1971 | |
| 62 | Cam Holliday | 127 | 1923-1927 | |
| 63 | Pedro Flores | 125 | 1944-1949 | |
| 63 | Ken Woods | 125 | 1976-1990 | |
| 65 | Matin bin Butrus | 123 | 1970-1978 | |
| 65 | Alfonso García | 123 | 1969-1974 | |
| 65 | Gary Lee | 123 | 1937-1939 | |
| 65 | Pancho Martínez | 123 | 1911-1911 | |
| 69 | Clarence Dean | 122 | 1984-1987 | |
| 69 | Terry Vanderven | 122 | 1946-1955 | |
| 71 | George Edwards | 121 | 1930-1942 | |
| 72 | Gustavo Quintero | 120 | 1940-1948 | |
| 73 | Armando Crespo | 119 | 1950-1954 | |
| 74 | Mark Burrows | 117 | 1912-1917 | |
| 75 | Todd Walsh | 116 | 1939-1946 | |
| 76 | Germán García | 115 | 1971-1976 | |
| 76 | John O'Cloonan | 115 | 1924-1929 | |
| 78 | Fred Lewis | 114 | 1915-1917 | |
| 78 | Dave López# | 114 | 1988-1991 | |
| 80 | Mus'ad bin Bursuq | 113 | 1975-1976 | |
| 81 | António Escobar | 112 | 1957-1957 | |
| 82 | António Guerra | 111 | 1962-1971 | |
| 83 | Mark Bishop | 110 | 1914-1915 | |
| 83 | John Strickland | 110 | 1916-1925 | |
| 85 | Raúl Francisco | 109 | 1921-1930 | |
| 85 | Roger Jones | 109 | 1930-1932 | |
| 87 | Andrés Nava | 108 | 1959-1976 | |
| 88 | Saula Marron | 107 | 1930-1937 | |
| 88 | Jesse McMillan | 107 | 1922-1925 | |
| 88 | Jeffery Osborne | 107 | 1924-1930 | |
| 91 | Milo MacPherson# | 105 | 1984-1988 | |
| 91 | Quinn Neal | 105 | 1975-1978 | |
| 91 | Francisco Pérez# | 105 | 1988-1988 | |
| 94 | Marcos Ramírez | 104 | 1945-1947 | |
| 95 | Mark Castile | 102 | 1978-1980 | |
| 95 | Greg Pérez | 102 | 1981-1984 | |
| 97 | Vicente Aguilera | 100 | 1912-1916 | |
| 97 | Bill Gross | 100 | 1974-1987 | |
| 99 | Scott George | 99 | 1913-1916 | |
| 99 | Lorenzo López | 99 | 1930-1932 |
