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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Francisco Moreno | 64 | 1915-1921 | |
| 1 | Chris Thompson | 64 | 1911-1916 | |
| 3 | Matt Brown | 54 | 1911-1914 | |
| 3 | Pantalian Torrinha | 54 | 1915-1925 | |
| 5 | Bob Browne# | 53 | 1985-1989 | |
| 6 | Sam Mohmand | 52 | 1929-1938 | |
| 7 | David Booth | 48 | 1912-1915 | |
| 7 | Robert Jones | 48 | 1982-1986 | |
| 9 | Eduardo González | 44 | 1911-1914 | |
| 9 | Brad Spencer | 44 | 1970-1980 | |
| 11 | Miguel Gonzáles | 40 | 1911-1918 | |
| 12 | Jed Love | 39 | 1912-1915 | |
| 12 | Conan Mercer | 39 | 1913-1921 | |
| 14 | Artie Baucom | 36 | 1959-1966 | |
| 14 | Joe Hess | 36 | 1977-1985 | |
| 14 | Neal Schaefer | 36 | 1975-1979 | |
| 17 | Jim Crowe | 34 | 1925-1934 | |
| 17 | Mike Wiggins# | 34 | 1979-1991 | |
| 19 | Patrick Delannoy | 33 | 1969-1973 | |
| 19 | Lorenzo Ruíz | 33 | 1957-1967 | |
| 21 | Adrian Johnson | 30 | 1911-1913 | |
| 21 | José Reyes | 30 | 1956-1966 | |
| 21 | Diego Rodríguez | 30 | 1940-1948 | |
| 24 | Júlio Antúnez | 29 | 1949-1950 | |
| 24 | Enrique Diéguez# | 29 | 1987-1991 | |
| 24 | José García | 29 | 1957-1962 | |
| 24 | Michael Hodges | 29 | 1912-1917 | |
| 24 | Melvin McKenzie | 29 | 1930-1939 | |
| 24 | Bartolo Rosas | 29 | 1958-1967 | |
| 24 | Ken Woods | 29 | 1976-1990 | |
| 31 | Joseph Battams# | 28 | 1988-1989 | |
| 31 | Román Robles | 28 | 1977-1990 | |
| 33 | Billy Smith | 27 | 1911-1913 | |
| 33 | Wilbert Whitaker | 27 | 1937-1946 | |
| 35 | Travis Brown | 26 | 1954-1961 | |
| 35 | Bill Delaney | 26 | 1943-1954 | |
| 35 | Juan García | 26 | 1930-1941 | |
| 35 | Cliff Greenwood | 26 | 1923-1930 | |
| 35 | Don Hudson | 26 | 1914-1921 | |
| 35 | Joe Morgan | 26 | 1957-1966 | |
| 35 | Héctor Palomarez# | 26 | 1984-1987 | |
| 35 | Marcos Sánchez | 26 | 1917-1919 | |
| 43 | Jack Bush# | 25 | 1985-1991 | |
| 43 | Salvador Gómez | 25 | 1951-1957 | |
| 43 | Brendon Jennings | 25 | 1911-1915 | |
| 43 | Steve McLaughlin | 25 | 1954-1965 | |
| 47 | Natsu Fujita | 24 | 1949-1956 | |
| 47 | Lorenzo Torres# | 24 | 1985-1988 | |
| 49 | Jorge Durán | 23 | 1912-1925 | |
| 49 | Mateus Mialheiro | 23 | 1916-1923 | |
| 51 | Eduardo Hernández | 22 | 1911-1913 | |
| 52 | Manuel Figueroa | 21 | 1978-1989 | |
| 52 | Jason Garrett | 21 | 1920-1928 | |
| 52 | Brian Hunter | 21 | 1966-1971 | |
| 52 | Manuel Rodríguez | 21 | 1911-1911 | |
| 52 | Pedro Torres | 21 | 1973-1985 | |
| 57 | Zachary King | 20 | 1911-1915 | |
| 57 | Gerardo Rivera# | 20 | 1985-1990 | |
| 57 | Tim Thackray# | 20 | 1990-1991 | |
| 60 | Juan Acevedo | 19 | 1963-1968 | |
| 60 | Mario García | 19 | 1917-1920 | |
| 60 | Carlos Helásquez | 19 | 1963-1975 | |
| 60 | José Montero | 19 | 1961-1963 | |
| 60 | Gustavo Quintero | 19 | 1940-1948 | |
| 60 | Alfonso Ríos | 19 | 1974-1976 | |
| 60 | John Strickland | 19 | 1916-1925 | |
| 60 | Lee Williams | 19 | 1974-1983 | |
| 68 | José Medrano | 18 | 1952-1953 | |
| 68 | Rafael Ruíz | 18 | 1973-1977 | |
| 68 | Jeffrey Thomas | 18 | 1948-1959 | |
| 71 | Esteban Anaya# | 17 | 1982-1988 | |
| 71 | Dan Barnett | 17 | 1945-1958 | |
| 71 | James Floyd | 17 | 1974-1981 | |
| 71 | John Giles | 17 | 1961-1961 | |
| 71 | Buddy Jamison | 17 | 1911-1919 | |
| 71 | Sung-keun Kim | 17 | 1938-1940 | |
| 71 | Christian McDougall# | 17 | 1987-1989 | |
| 71 | Darren Morgenstern# | 17 | 1984-1989 | |
| 71 | Ed Reynolds | 17 | 1915-1921 | |
| 71 | Héctor Rodríguez | 17 | 1952-1958 | |
| 71 | Darryl Wolf | 17 | 1985-1988 | |
| 82 | Pedro Bernal | 16 | 1947-1961 | |
| 82 | Ed Bush | 16 | 1913-1921 | |
| 82 | Lowell Hardy | 16 | 1945-1950 | |
| 82 | Forest Murphy | 16 | 1912-1915 | |
| 82 | Denzel Popham | 16 | 1917-1918 | |
| 82 | David Reese# | 16 | 1984-1988 | |
| 82 | Takeichi Yamashita | 16 | 1939-1945 | |
| 89 | Drake Day# | 15 | 1982-1982 | |
| 89 | Gustaf Egberts | 15 | 1974-1981 | |
| 89 | José Flores | 15 | 1944-1946 | |
| 89 | Luis Gómez# | 15 | 1980-1990 | |
| 89 | Yoshimochi Miyamoto | 15 | 1952-1961 | |
| 89 | Manuel Muñóz | 15 | 1953-1962 | |
| 89 | Gabriel Núñez | 15 | 1911-1911 | |
| 89 | Salvador Palmeiro | 15 | 1950-1956 | |
| 89 | John Peters | 15 | 1912-1916 | |
| 89 | Roberto Pinto | 15 | 1920-1923 | |
| 89 | Gabriel Rivera | 15 | 1917-1917 | |
| 89 | Juan Jose Rodríguez | 15 | 1978-1985 |
