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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | George Goodwin | 56 | 1975-1979 | |
| 2 | Luis Carmona | 54 | 1957-1963 | |
| 3 | José Cabral# | 51 | 1975-1981 | |
| 4 | Miguel Longoria | 48 | 1912-1914 | |
| 5 | Phil Carter | 46 | 1975-1986 | |
| 6 | Chris Mathews | 44 | 1912-1914 | |
| 6 | Thierry Robert# | 44 | 1976-1987 | |
| 8 | Alberto Cervantes# | 43 | 1986-1989 | |
| 8 | Jun-ho Park# | 43 | 1986-1988 | |
| 8 | Stephen Willis | 43 | 1911-1912 | |
| 11 | José Hernández | 42 | 1959-1963 | |
| 12 | António Canseco | 41 | 1959-1961 | |
| 12 | Habte Dunde | 41 | 1912-1914 | |
| 12 | Wyatt Newman | 41 | 1957-1960 | |
| 15 | David Nichols | 40 | 1976-1978 | |
| 15 | Brad O'Cawley | 40 | 1964-1965 | |
| 15 | António Pérez | 40 | 1959-1962 | |
| 15 | Manuel Pérez | 40 | 1979-1987 | |
| 15 | Charlie Reid# | 40 | 1983-1989 | |
| 15 | Edgardo Sandoval | 40 | 1970-1974 | |
| 15 | Te Shih | 40 | 1975-1985 | |
| 22 | Raúl Gonzáles | 39 | 1975-1978 | |
| 22 | Dave Jordan# | 39 | 1984-1987 | |
| 24 | Graham Brooks | 38 | 1970-1972 | |
| 24 | Mario Gonzáles | 38 | 1952-1954 | |
| 26 | Santiago Azcarreta# | 37 | 1976-1979 | |
| 26 | Leroy Bek | 37 | 1975-1986 | |
| 26 | Nick Cockshutt | 37 | 1911-1916 | |
| 26 | Emílio Román | 37 | 1945-1949 | |
| 26 | Jud Warner# | 37 | 1987-1990 | |
| 31 | Lyle Decker | 36 | 1952-1957 | |
| 31 | Brad Ford# | 36 | 1981-1986 | |
| 31 | Phil Lucas# | 36 | 1979-1983 | |
| 34 | Daniel Garegnani | 35 | 1951-1953 | |
| 34 | José Hernández# | 35 | 1975-1977 | |
| 34 | Carlos Lugo | 35 | 1914-1917 | |
| 34 | Luis Ramos# | 35 | 1984-1985 | |
| 34 | Duane Richardson | 35 | 1911-1915 | |
| 34 | John Smith | 35 | 1911-1912 | |
| 40 | Eduardo Caprioglio# | 34 | 1979-1983 | |
| 40 | Paco Chávez# | 34 | 1981-1987 | |
| 40 | Mike Curry | 34 | 1912-1915 | |
| 40 | Miguel Guerra# | 34 | 1975-1990 | |
| 40 | Bryan Miles | 34 | 1966-1969 | |
| 40 | Salif Msamaki | 34 | 1971-1974 | |
| 40 | Konosuke Okada | 34 | 1973-1987 | |
| 40 | Pablo Ortíz | 34 | 1967-1970 | |
| 40 | Fernando Soto | 34 | 1976-1983 | |
| 40 | Alberto Torres | 34 | 1956-1959 | |
| 50 | Ángel Alvarado | 33 | 1965-1969 | |
| 50 | Domingo Gallegos | 33 | 1971-1974 | |
| 50 | Michael Halliburton | 33 | 1912-1914 | |
| 50 | Augusto Vélez | 33 | 1975-1979 | |
| 54 | Francisco Alston# | 32 | 1978-1982 | |
| 54 | Carroll Blackburn | 32 | 1911-1914 | |
| 54 | Jeff Conway | 32 | 1979-1982 | |
| 54 | Juan Peralta | 32 | 1978-1982 | |
| 54 | Jorge Relgio | 32 | 1963-1969 | |
| 54 | Sean Tobias | 32 | 1912-1916 | |
| 60 | Lane Alexander | 31 | 1957-1962 | |
| 60 | Milo MacPherson# | 31 | 1979-1982 | |
| 60 | Carlos Martínez | 31 | 1967-1972 | |
| 60 | Francisco Orellamo# | 31 | 1983-1985 | |
| 64 | Joaquín Amésquita | 30 | 1975-1980 | |
| 64 | Luis Castro# | 30 | 1982-1985 | |
| 64 | Aldomiro Centeeiro | 30 | 1914-1916 | |
| 64 | Fidelio Coriolano | 30 | 1911-1912 | |
| 64 | Corbett Ellis | 30 | 1916-1917 | |
| 64 | António Gómez# | 30 | 1977-1979 | |
| 64 | Steve Holmes | 30 | 1912-1916 | |
| 64 | Stanley Jackson | 30 | 1939-1942 | |
| 64 | Rob Lee | 30 | 1916-1917 | |
| 64 | Manny Márquez | 30 | 1957-1960 | |
| 64 | Leo Marshall | 30 | 1957-1959 | |
| 64 | Manny Negrón | 30 | 1957-1963 | |
| 64 | Eduardo Vázquez | 30 | 1975-1979 | |
| 77 | Ricardo Flores | 29 | 1957-1961 | |
| 77 | José Hernández | 29 | 1975-1977 | |
| 77 | Adam Rivas | 29 | 1913-1916 | |
| 77 | Nasih Sariyah | 29 | 1970-1972 | |
| 77 | Luis Vargas | 29 | 1957-1962 | |
| 77 | Guonçalle Vilo# | 29 | 1981-1984 | |
| 83 | Jon Collins# | 28 | 1987-1989 | |
| 83 | Daryl Combs | 28 | 1970-1973 | |
| 83 | Carolan Farquhar | 28 | 1926-1930 | |
| 83 | Pat Hayes# | 28 | 1985-1988 | |
| 83 | Harry Lee | 28 | 1969-1973 | |
| 83 | Jesse Logan | 28 | 1958-1960 | |
| 83 | Reggie Long | 28 | 1976-1980 | |
| 83 | Carlos López# | 28 | 1986-1988 | |
| 83 | Júlio Miranda | 28 | 1966-1969 | |
| 83 | Jerry Olson# | 28 | 1983-1987 | |
| 83 | Mike Payne# | 28 | 1979-1983 | |
| 83 | Billy Thomas | 28 | 1957-1960 | |
| 95 | John Andrés# | 27 | 1981-1985 | |
| 95 | Emílio Córdova# | 27 | 1979-1982 | |
| 95 | José González | 27 | 1976-1979 | |
| 95 | Jeff Keys# | 27 | 1979-1982 | |
| 95 | Jorge Ramírez# | 27 | 1988-1988 | |
| 95 | Ron Roy | 27 | 1961-1965 |
