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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Miguel Longoria | 48 | 1912-1914 | |
| 2 | António Canseco | 41 | 1959-1961 | |
| 3 | Graham Brooks | 38 | 1970-1972 | |
| 4 | Lyle Decker | 36 | 1952-1957 | |
| 5 | Alberto Torres | 34 | 1956-1959 | |
| 6 | Domingo Gallegos | 33 | 1971-1974 | |
| 7 | Lane Alexander | 31 | 1957-1962 | |
| 8 | Aldomiro Centeeiro | 30 | 1914-1916 | |
| 8 | Eduardo Vázquez | 30 | 1975-1979 | |
| 10 | Reggie Long | 28 | 1976-1980 | |
| 10 | Júlio Miranda | 28 | 1966-1969 | |
| 12 | Mark Bursey | 26 | 1951-1953 | |
| 12 | Bob Ryan# | 26 | 1977-1979 | |
| 14 | Ta-heng Jiang# | 25 | 1981-1983 | |
| 14 | Dana Raymond | 25 | 1950-1953 | |
| 16 | Rob Barnard# | 23 | 1983-1984 | |
| 16 | Perry Dean | 23 | 1954-1955 | |
| 16 | Bill Harvey | 23 | 1961-1962 | |
| 19 | Perry Hampton | 22 | 1948-1949 | |
| 20 | Milford Coe | 21 | 1916-1917 | |
| 20 | Javier De Fiesta | 21 | 1980-1989 | |
| 20 | Rafael Martínez | 21 | 1974-1978 | |
| 20 | Lorenzo Navarro | 21 | 1912-1914 | |
| 20 | Baltwin Young | 21 | 1971-1973 | |
| 25 | Cal Anderson | 20 | 1947-1949 | |
| 26 | José Gonzáles | 19 | 1946-1948 | |
| 26 | José Hernández | 19 | 1911-1912 | |
| 26 | Luis Rodríguez# | 19 | 1984-1989 | |
| 26 | Les Watson | 19 | 1972-1978 | |
| 30 | Scott Fitzgerald | 18 | 1973-1987 | |
| 30 | Dharam Kutty | 18 | 1975-1978 | |
| 30 | Lupe Lerma | 18 | 1911-1914 | |
| 30 | Tom Mills# | 18 | 1976-1978 | |
| 30 | Richard Smith | 18 | 1976-1980 | |
| 30 | Fernando Tores | 18 | 1967-1969 | |
| 30 | Adrian Walcott | 18 | 1955-1957 | |
| 37 | Javier Cabrera# | 17 | 1978-1983 | |
| 37 | Henry Chandler | 17 | 1930-1942 | |
| 37 | Roberto De La Garza | 17 | 1911-1912 | |
| 37 | Ewan Mclean | 17 | 1927-1932 | |
| 37 | Orlando Ramos | 17 | 1975-1985 | |
| 37 | Claudio Santana# | 17 | 1983-1986 | |
| 43 | Eric Carter | 16 | 1971-1972 | |
| 43 | Javier De La Cruz | 16 | 1934-1942 | |
| 43 | Juan Estrada | 16 | 1939-1941 | |
| 43 | Kevin Keller | 16 | 1940-1942 | |
| 43 | Roberto Lerma | 16 | 1920-1923 | |
| 43 | Cris Mejía | 16 | 1913-1915 | |
| 43 | Dan Olson | 16 | 1973-1974 | |
| 43 | Lian-wei Ow-Yang | 16 | 1961-1965 | |
| 43 | Francisco Peña | 16 | 1952-1953 | |
| 43 | Félix Pérez | 16 | 1929-1930 | |
| 43 | Perry Robinson# | 16 | 1983-1986 | |
| 54 | Louis Casas | 15 | 1973-1974 | |
| 54 | Carlos Díaz | 15 | 1912-1912 | |
| 54 | Tom Holt | 15 | 1945-1948 | |
| 54 | Carlos Johnson | 15 | 1981-1989 | |
| 54 | Pete Rodríguez# | 15 | 1987-1989 | |
| 54 | José Sánchez | 15 | 0-0 | |
| 54 | Edward Walters | 15 | 1970-1971 | |
| 61 | Arturo Carrillo | 14 | 1980-1990 | |
| 61 | Anastasio Domínguez | 14 | 1975-1976 | |
| 61 | Walt Elliott | 14 | 1911-1912 | |
| 61 | Dusty Gardner | 14 | 1929-1932 | |
| 61 | Harley Griggs | 14 | 1950-1951 | |
| 61 | Tom Heller | 14 | 1971-1972 | |
| 61 | Steve Long | 14 | 1974-1977 | |
| 61 | Sanya Madatov | 14 | 1981-1981 | |
| 61 | Artie Martin | 14 | 1927-1929 | |
| 61 | Eric Powell | 14 | 1911-1913 | |
| 61 | José Recéndis | 14 | 1967-1969 | |
| 61 | Sergio Rivera | 14 | 1955-1957 | |
| 61 | Esteban Sandoval# | 14 | 1977-1980 | |
| 61 | Jeffrey Vinson | 14 | 1915-1919 | |
| 61 | Alec Wilson | 14 | 1975-1987 | |
| 61 | Jerome Wright | 14 | 1939-1940 | |
| 77 | Gustaf Bijl | 13 | 1932-1932 | |
| 77 | Rick Coker | 13 | 1935-1936 | |
| 77 | Mike Farmer | 13 | 1976-1977 | |
| 77 | Brian Johnson | 13 | 1940-1940 | |
| 77 | Ramón Martínez | 13 | 1955-1957 | |
| 77 | Darby Porter | 13 | 1956-1967 | |
| 77 | Dave Ross | 13 | 1913-1913 | |
| 77 | Lane Smith | 13 | 1930-1931 | |
| 77 | Buck Swanson | 13 | 1920-1922 | |
| 77 | Basilio Viera# | 13 | 1975-1976 | |
| 87 | Jesús Ávila# | 12 | 1983-1990 | |
| 87 | Enrique Baca | 12 | 1940-1942 | |
| 87 | Randy Bailey | 12 | 1951-1954 | |
| 87 | Pete Beard | 12 | 1973-1974 | |
| 87 | Ramón Colón | 12 | 1970-1973 | |
| 87 | Don Hensley | 12 | 1973-1976 | |
| 87 | Pete Hoover | 12 | 1911-1911 | |
| 87 | Dan Hummel | 12 | 1921-1923 | |
| 87 | Mink Ijzendoorn | 12 | 1958-1964 | |
| 87 | Chris Kessler | 12 | 1978-1979 | |
| 87 | Felix Levasier | 12 | 1961-1963 | |
| 87 | José Luna | 12 | 1912-1915 | |
| 87 | Álex Mata | 12 | 1951-1965 | |
| 87 | Charles Matthews | 12 | 1942-1944 |
