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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | José Cabral# | 51 | 1975-1981 | |
| 2 | Jun-ho Park# | 43 | 1986-1988 | |
| 3 | António Pérez | 40 | 1959-1962 | |
| 3 | Manuel Pérez | 40 | 1979-1987 | |
| 5 | Dave Jordan# | 39 | 1984-1987 | |
| 6 | Emílio Román | 37 | 1945-1949 | |
| 6 | Jud Warner# | 37 | 1987-1990 | |
| 8 | José Hernández# | 35 | 1975-1977 | |
| 9 | Eduardo Caprioglio# | 34 | 1979-1983 | |
| 10 | Habte Dunde | 33 | 1912-1914 | |
| 11 | Joaquín Amésquita | 30 | 1975-1980 | |
| 11 | Stanley Jackson | 30 | 1939-1942 | |
| 11 | Rob Lee | 30 | 1916-1917 | |
| 11 | Manny Márquez | 30 | 1957-1960 | |
| 11 | Leo Marshall | 30 | 1957-1959 | |
| 16 | Emílio Córdova# | 27 | 1979-1982 | |
| 17 | Paul Anderson | 26 | 1911-1913 | |
| 17 | Brad Ford# | 26 | 1981-1986 | |
| 19 | Bill Ford | 25 | 1966-1970 | |
| 19 | Mark Wilson | 25 | 1950-1951 | |
| 21 | Wilber Hill# | 24 | 1984-1987 | |
| 21 | Jeff Jackson | 24 | 1954-1954 | |
| 21 | Stanley Lucas# | 24 | 1975-1976 | |
| 21 | Gabriel Montoya | 24 | 1917-1917 | |
| 21 | Jorge Sánchez | 24 | 1934-1935 | |
| 26 | Steven Chapman | 23 | 1911-1915 | |
| 26 | Alejandro Hernández | 23 | 1950-1952 | |
| 26 | Vincent Jarvis | 23 | 1958-1960 | |
| 26 | Marvin Savage | 23 | 1963-1969 | |
| 30 | Benjamin Buggs | 22 | 1955-1961 | |
| 30 | Fidelio Coriolano | 22 | 1911-1912 | |
| 30 | Nelson Davis | 22 | 1966-1968 | |
| 30 | Cory Hernández | 22 | 1972-1973 | |
| 30 | Udo Herz | 22 | 1977-1977 | |
| 30 | Kade Kraft | 22 | 1916-1922 | |
| 36 | Manny Acosta | 21 | 1912-1913 | |
| 36 | Xavier López | 21 | 1951-1951 | |
| 36 | Esteban Maldonado# | 21 | 1978-1990 | |
| 36 | Pat Sullivan | 21 | 1963-1966 | |
| 36 | George Wagner | 21 | 1961-1962 | |
| 41 | Bill Cole# | 20 | 1980-1981 | |
| 41 | Matt James | 20 | 1974-1974 | |
| 41 | Yasunobu Kokura | 20 | 1958-1960 | |
| 41 | José Salgado | 20 | 1966-1968 | |
| 41 | Millard Whitaker# | 20 | 1977-1990 | |
| 46 | Miguel Castro | 19 | 1914-1915 | |
| 46 | Carlos González | 19 | 1965-1966 | |
| 46 | Félix González | 19 | 1973-1974 | |
| 46 | Miguel Guzmán | 19 | 1953-1960 | |
| 46 | Raúl Miranda | 19 | 1972-1973 | |
| 46 | Aaron Morgan | 19 | 1911-1912 | |
| 46 | Juan Rodríguez | 19 | 1946-1949 | |
| 46 | Chance Saunders | 19 | 1961-1963 | |
| 54 | Samuel Bramati | 18 | 1937-1939 | |
| 54 | Juan Castro# | 18 | 1987-1989 | |
| 54 | Emílio Gallegos# | 18 | 1981-1982 | |
| 54 | Jesús González | 18 | 1953-1954 | |
| 54 | Theodore Jensen | 18 | 1950-1953 | |
| 54 | Carlos López# | 18 | 1982-1986 | |
| 54 | Javier Oliva | 18 | 1966-1969 | |
| 61 | Carlos Arenas | 17 | 1912-1914 | |
| 61 | Bialy Bartnik | 17 | 1964-1965 | |
| 61 | Erik Fisher | 17 | 1985-1990 | |
| 61 | Edgardo Flores | 17 | 1963-1964 | |
| 61 | Whit Hudson# | 17 | 1982-1987 | |
| 61 | Roy Jackson# | 17 | 1980-1980 | |
| 61 | Gil LeMond# | 17 | 1980-1982 | |
| 61 | Glenn Summers# | 17 | 1977-1981 | |
| 69 | Héctor Acevedo | 16 | 1975-1976 | |
| 69 | Guy Davis | 16 | 1911-1912 | |
| 69 | Riley Harden | 16 | 1963-1965 | |
| 69 | Bob Henry | 16 | 1978-1988 | |
| 69 | Fraser MacKellar | 16 | 1927-1928 | |
| 69 | Dale Mooney# | 16 | 1979-1979 | |
| 69 | Luis Rodríguez | 16 | 1936-1939 | |
| 69 | Francisco Romano | 16 | 1912-1921 | |
| 69 | Mike Sugden# | 16 | 1982-1985 | |
| 69 | Phil Thompson | 16 | 1966-1971 | |
| 69 | Theodore White | 16 | 1950-1951 | |
| 80 | Allen Caldwell | 15 | 1956-1958 | |
| 80 | Henry Crawford | 15 | 1914-1916 | |
| 80 | Alberto Gonzáles | 15 | 1916-1919 | |
| 80 | Domingo Hernández | 15 | 1937-1937 | |
| 80 | Donald Owens | 15 | 1967-1969 | |
| 80 | Nasih Sariyah | 15 | 1970-1972 | |
| 80 | Motoki Sato# | 15 | 1990-1990 | |
| 80 | António Sosa# | 15 | 1986-1986 | |
| 80 | Kyle Walker | 15 | 1915-1916 | |
| 89 | Craig Anderson | 14 | 1977-1981 | |
| 89 | Rob Bailey | 14 | 1935-1939 | |
| 89 | Arthur Barnes | 14 | 1964-1967 | |
| 89 | George Crosby | 14 | 1968-1971 | |
| 89 | Mike Greene | 14 | 1956-1959 | |
| 89 | Lance Henderson | 14 | 1966-1967 | |
| 89 | Edgar Morton | 14 | 1974-1977 | |
| 89 | David Nichols | 14 | 1976-1978 | |
| 89 | Larry O'Brian | 14 | 1972-1973 | |
| 89 | Freddy Pérez | 14 | 1955-1957 | |
| 89 | Vicente Ramos | 14 | 1954-1957 | |
| 89 | Arturo Rico | 14 | 1940-1941 |
