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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Luis Carmona | 54 | 1957-1963 | |
| 2 | Alberto Cervantes# | 43 | 1986-1989 | |
| 3 | George Goodwin | 42 | 1975-1979 | |
| 4 | Brad O'Cawley | 40 | 1964-1965 | |
| 5 | Ángel Alvarado | 33 | 1965-1969 | |
| 5 | Augusto Vélez | 33 | 1975-1979 | |
| 7 | Carroll Blackburn | 32 | 1911-1914 | |
| 7 | Juan Peralta | 32 | 1978-1982 | |
| 9 | Jeff Conway | 29 | 1979-1982 | |
| 9 | José Hernández | 29 | 1975-1977 | |
| 11 | Mike Payne# | 28 | 1979-1983 | |
| 12 | Maxime Pelletier | 26 | 1976-1980 | |
| 12 | Rijk Victorie | 26 | 1967-1971 | |
| 14 | Gavin Banks | 25 | 1945-1949 | |
| 14 | Zach Rice | 25 | 1983-1988 | |
| 16 | Paul Latham | 24 | 1979-1980 | |
| 16 | José Lieftinck | 24 | 1949-1963 | |
| 16 | Mike Powell# | 24 | 1983-1984 | |
| 16 | Tim Ware# | 24 | 1977-1980 | |
| 16 | Ray Wright# | 24 | 1988-1990 | |
| 21 | Justin Calderón | 23 | 1978-1988 | |
| 22 | Francisco Delgado | 22 | 1973-1974 | |
| 22 | Adam Rivas | 22 | 1913-1916 | |
| 24 | Michael Blake# | 21 | 1976-1978 | |
| 24 | Tim Johnson# | 21 | 1985-1988 | |
| 24 | Francisco Trevino | 21 | 1917-1919 | |
| 27 | Víctor Guerrero | 20 | 1964-1965 | |
| 27 | Andrés Gutiérrez# | 20 | 1988-1989 | |
| 27 | Arturo Longoria | 20 | 1971-1972 | |
| 27 | Carter Manns | 20 | 1975-1983 | |
| 27 | José Ríos | 20 | 1970-1972 | |
| 27 | Axel Teschendorff | 20 | 1928-1931 | |
| 33 | Juan Bernal | 19 | 1970-1971 | |
| 33 | Benedicto Castillo | 19 | 1973-1987 | |
| 33 | Matt Gordon | 19 | 1934-1942 | |
| 33 | Christian Hall | 19 | 1969-1970 | |
| 33 | Pete Hernández# | 19 | 1983-1985 | |
| 33 | Takamasa Kakuta | 19 | 1962-1964 | |
| 33 | Daniel Rodríguez | 19 | 1956-1960 | |
| 40 | Juan García | 18 | 1973-1974 | |
| 40 | Alfredo Guerra | 18 | 1954-1955 | |
| 40 | Gus Miller | 18 | 1956-1962 | |
| 40 | José Prieto | 18 | 1976-1976 | |
| 40 | Gilberto Rodríguez | 18 | 1968-1972 | |
| 40 | Everett Sawyer | 18 | 1972-1973 | |
| 40 | Gil Snyder | 18 | 1956-1958 | |
| 40 | Ellis Stallard | 18 | 1916-1916 | |
| 40 | Pedro Torres | 18 | 1954-1956 | |
| 40 | Paul Warren | 18 | 1912-1913 | |
| 50 | Pedro Gallegos | 17 | 1962-1964 | |
| 50 | Paul Green | 17 | 1949-1950 | |
| 50 | Konosuke Okada | 17 | 1973-1987 | |
| 50 | Víctor Rodríguez | 17 | 1958-1964 | |
| 50 | Doug Thompson | 17 | 1952-1955 | |
| 55 | Bennett Davis | 16 | 1961-1963 | |
| 55 | Brad Kinchen | 16 | 1974-1974 | |
| 55 | Brandon Ramsey | 16 | 1957-1959 | |
| 55 | Bernie Rowe | 16 | 1970-1971 | |
| 55 | Brian Thomas | 16 | 1912-1912 | |
| 55 | Ted Thomas | 16 | 1912-1912 | |
| 55 | Claudio Valdéz | 16 | 1930-1933 | |
| 55 | Guonçalle Vilo# | 16 | 1981-1984 | |
| 63 | Gene Davis | 15 | 1952-1952 | |
| 63 | Alberto Gómez | 15 | 1981-1983 | |
| 63 | Rodney Hall | 15 | 1967-1970 | |
| 63 | Lyndon Hunt | 15 | 1981-1989 | |
| 63 | Keith Message | 15 | 1914-1915 | |
| 63 | Jim Rankin | 15 | 1966-1967 | |
| 63 | Felipe Rodríguez | 15 | 1970-1971 | |
| 63 | Francisco Salaza | 15 | 1912-1915 | |
| 71 | Javier Acosta | 14 | 1967-1969 | |
| 71 | Bill Burnett# | 14 | 1987-1989 | |
| 71 | Kevin Burrell | 14 | 1952-1953 | |
| 71 | Luis Castro# | 14 | 1982-1985 | |
| 71 | Rafael Duarte | 14 | 1954-1960 | |
| 71 | Luis Hernández | 14 | 1917-1917 | |
| 71 | José Iñigo | 14 | 1930-1931 | |
| 71 | Austin Johnson | 14 | 1953-1954 | |
| 71 | Guy Knight | 14 | 1965-1968 | |
| 71 | Carlos Latorro# | 14 | 1980-1982 | |
| 71 | Félix Mansanarez | 14 | 1941-1943 | |
| 71 | Stu Martin | 14 | 1914-1915 | |
| 71 | Félix Salinas | 14 | 1952-1954 | |
| 71 | Nasih Sariyah | 14 | 1970-1972 | |
| 71 | Calvin Smith | 14 | 1972-1973 | |
| 71 | Francisco Vargas# | 14 | 1975-1977 | |
| 87 | Raúl Ayers | 13 | 1953-1954 | |
| 87 | Greg Butler# | 13 | 1983-1990 | |
| 87 | Juan Carrillo | 13 | 1940-1940 | |
| 87 | José Fajards | 13 | 1957-1960 | |
| 87 | Luis Gil# | 13 | 1982-1982 | |
| 87 | Francisco Hidalgo | 13 | 1930-1932 | |
| 87 | Jen-djieh Kwan | 13 | 1955-1958 | |
| 87 | Alonso Martínez# | 13 | 1988-1989 | |
| 87 | Carl Matena# | 13 | 1980-1981 | |
| 87 | Jaime Mejines# | 13 | 1987-1989 | |
| 87 | Víctor Molina | 13 | 1964-1977 | |
| 87 | Paul Owens | 13 | 1950-1951 | |
| 87 | José Palmeiro# | 13 | 1976-1977 | |
| 87 | Javier Peña | 13 | 1938-1941 |
