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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Chris Mathews | 44 | 1912-1914 | |
| 2 | Charlie Reid# | 40 | 1983-1989 | |
| 3 | Daniel Garegnani | 35 | 1951-1953 | |
| 3 | Luis Ramos# | 35 | 1984-1985 | |
| 5 | Milo MacPherson# | 31 | 1979-1982 | |
| 5 | Francisco Orellamo# | 31 | 1983-1985 | |
| 7 | Corbett Ellis | 30 | 1916-1917 | |
| 8 | Phil Carter | 29 | 1975-1986 | |
| 8 | Luis Vargas | 29 | 1957-1962 | |
| 10 | Carlos López# | 28 | 1986-1988 | |
| 10 | Jerry Olson# | 28 | 1983-1987 | |
| 12 | Jorge Ramírez# | 27 | 1988-1988 | |
| 13 | Jorge Alvarado | 26 | 1963-1965 | |
| 13 | Joseph Nicholson | 26 | 1950-1952 | |
| 13 | Malcolm Paige | 26 | 1961-1963 | |
| 13 | Mike Rúbio | 26 | 1953-1954 | |
| 17 | Juan García | 25 | 1950-1951 | |
| 18 | Bob Corbin | 24 | 1963-1964 | |
| 18 | Bastien Sanguinacco# | 24 | 1981-1984 | |
| 20 | Steven Powell# | 23 | 1977-1979 | |
| 20 | Ernest Snow | 23 | 1975-1978 | |
| 22 | Fernando Méndez | 22 | 1955-1956 | |
| 23 | Jon Collins# | 21 | 1987-1989 | |
| 23 | Nunno Jarava | 21 | 1979-1988 | |
| 23 | Mike Young | 21 | 1912-1912 | |
| 26 | Randy de Lange | 20 | 1979-1981 | |
| 26 | Don Harper | 20 | 1964-1965 | |
| 26 | Ken McCarty | 20 | 1973-1974 | |
| 29 | Lorenzo Barrera | 19 | 1912-1912 | |
| 29 | Ron Marks | 19 | 1957-1960 | |
| 29 | Christian Wilson | 19 | 1960-1965 | |
| 32 | Ronnie Edwards | 18 | 1941-1943 | |
| 32 | Chris Massey | 18 | 1951-1953 | |
| 34 | Jeff Dougherty | 17 | 1982-1989 | |
| 34 | Orlando Gastelo# | 17 | 1988-1990 | |
| 34 | Santiago Herrera | 17 | 1976-1987 | |
| 34 | Víctor Padilla | 17 | 1911-1912 | |
| 34 | António Pérez | 17 | 1976-1987 | |
| 34 | Arturo Ramos | 17 | 1977-1977 | |
| 34 | José Robles | 17 | 1912-1913 | |
| 41 | Joe Andrews | 16 | 1952-1959 | |
| 41 | Barnabas Drescher | 16 | 1948-1954 | |
| 41 | Vincente García# | 16 | 1986-1990 | |
| 41 | Juan Pérez | 16 | 1945-1946 | |
| 41 | Henry Segaar | 16 | 1927-1930 | |
| 41 | Andrew Solley | 16 | 1913-1914 | |
| 41 | Roland Williamson | 16 | 1966-1972 | |
| 41 | Stephen Willis | 16 | 1911-1912 | |
| 49 | José Carrillo# | 15 | 1982-1982 | |
| 49 | Theodore Dobson | 15 | 1950-1953 | |
| 49 | César Gil | 15 | 1953-1955 | |
| 49 | Herman Hancock | 15 | 1952-1952 | |
| 49 | Bartolo Luna | 15 | 1945-1948 | |
| 49 | Juan Martínez | 15 | 1928-1929 | |
| 49 | Quinn Neal | 15 | 1972-1973 | |
| 49 | Trevor Ruffin | 15 | 1966-1967 | |
| 49 | Henry Sullivan# | 15 | 1980-1980 | |
| 58 | Valentín Aguilar | 14 | 1970-1971 | |
| 58 | Gunner Ashby | 14 | 1973-1990 | |
| 58 | Michael Craft | 14 | 1937-1939 | |
| 58 | Ramón García | 14 | 1977-1979 | |
| 58 | George Goodwin | 14 | 1975-1979 | |
| 58 | Arend Groenevelt | 14 | 1964-1966 | |
| 58 | Jaime Guzmán | 14 | 1946-1949 | |
| 58 | Ryan Hale | 14 | 1930-1933 | |
| 58 | Luis Hernández | 14 | 1951-1952 | |
| 58 | Carlos Lozano | 14 | 1975-1987 | |
| 58 | Yuki Matsushita | 14 | 1955-1956 | |
| 58 | Román Padilla# | 14 | 1988-1990 | |
| 58 | Cristián Trujillo | 14 | 1951-1951 | |
| 58 | Rubén Vega | 14 | 1967-1969 | |
| 58 | Arnie Wilkerson# | 14 | 1975-1976 | |
| 58 | Mike Wolf | 14 | 1919-1924 | |
| 74 | Dave Barton | 13 | 1979-1988 | |
| 74 | Ricardo Flores | 13 | 1957-1961 | |
| 74 | Zeke Flynn | 13 | 1913-1914 | |
| 74 | Daniel Green | 13 | 1940-1941 | |
| 74 | Héctor Guerrero | 13 | 1936-1940 | |
| 74 | Harry Jones | 13 | 1979-1982 | |
| 74 | Oscar Kennedy | 13 | 1938-1940 | |
| 74 | Jonathan King | 13 | 1963-1963 | |
| 74 | Víctor Maldonado | 13 | 1955-1968 | |
| 74 | John Miller | 13 | 1966-1968 | |
| 74 | Warner Phillips | 13 | 1954-1955 | |
| 74 | Doug Rivas | 13 | 1927-1929 | |
| 74 | Guonçalle Vilo# | 13 | 1981-1984 | |
| 74 | Mu'ammar Zahor# | 13 | 1981-1983 | |
| 88 | Allen Chatterton | 12 | 1947-1949 | |
| 88 | Ben Dooley# | 12 | 1980-1981 | |
| 88 | Eduardo Durán | 12 | 1921-1923 | |
| 88 | William Evans | 12 | 1978-1979 | |
| 88 | Richard Hebert | 12 | 1971-1971 | |
| 88 | Zuo-qian Lee | 12 | 1930-1937 | |
| 88 | Royce Morris | 12 | 1981-1988 | |
| 88 | Bob Parkinson | 12 | 1921-1923 | |
| 88 | Ashwin Peper# | 12 | 1979-1981 | |
| 88 | Yin-ti Phan | 12 | 1981-1989 | |
| 88 | Roberto Pinto | 12 | 1916-1917 | |
| 88 | Jorge Rivera | 12 | 1937-1939 | |
| 88 | Luis Rosales | 12 | 1942-1944 |
