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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Fernando Méndez | 592 | 1956 | |
| 2 | Luis Vargas | 584 | 1962 | |
| 3 | Fabroni Aguzzi | 579 | 1954 | |
| 4 | Jerry Olson# | 577 | 1984 | |
| 5 | Chris Massey | 576 | 1953 | |
| 5 | Joseph Nicholson | 576 | 1950 | |
| 7 | Joe Andrews | 575 | 1958 | |
| 7 | Mike Wolf | 575 | 1924 | |
| 9 | Luis Vargas | 572 | 1961 | |
| 9 | Mike MacIntosh# | 572 | 1983 | |
| 11 | Greg Owens | 570 | 1933 | |
| 12 | Trevor Ruffin | 569 | 1966 | |
| 13 | Armando García | 568 | 1933 | |
| 13 | Mike Rúbio | 568 | 1954 | |
| 13 | Carl Bradley | 568 | 1970 | |
| 16 | António Pérez | 567 | 1977 | |
| 17 | Alfonso Sanora | 566 | 1965 | |
| 17 | Doug Thornton# | 566 | 1979 | |
| 17 | Ron Jones | 566 | 1957 | |
| 20 | King Warren | 565 | 1986 | |
| 20 | Gabriel Bowles# | 565 | 1989 | |
| 20 | Bryant Simpson# | 565 | 1987 | |
| 23 | Martín Estrada | 564 | 1971 | |
| 23 | César Gil | 564 | 1954 | |
| 23 | Jesse Jordan | 564 | 1970 | |
| 26 | Bastien Sanguinacco# | 563 | 1983 | |
| 27 | Royce Morris | 562 | 1981 | |
| 28 | Jerry Olson# | 561 | 1983 | |
| 28 | Javier Negrete | 561 | 1962 | |
| 30 | Joe Knowles# | 560 | 1987 | |
| 30 | Milo MacPherson# | 560 | 1981 | |
| 30 | José Carrillo# | 560 | 1982 | |
| 33 | Dave Barton | 559 | 1982 | |
| 33 | Ernesto Gámez | 559 | 1975 | |
| 35 | David Murray# | 558 | 1986 | |
| 35 | Dana Jensen | 558 | 1939 | |
| 35 | Juan Elías# | 558 | 1978 | |
| 35 | Jorge Alvarado | 558 | 1965 | |
| 35 | Mu'ammar Zahor# | 558 | 1983 | |
| 40 | Mike Urmston Jr. | 557 | 1958 | |
| 41 | Jeff Dougherty | 556 | 1983 | |
| 42 | Christian Quint | 555 | 1968 | |
| 42 | Dan Bryant | 555 | 1972 | |
| 44 | Corbett Ellis | 554 | 1917 | |
| 44 | Wilson Gwyther | 554 | 1967 | |
| 46 | Jaime Guzmán | 553 | 1947 | |
| 47 | Ken McCarty | 552 | 1973 | |
| 47 | Mike Wolf | 552 | 1921 | |
| 49 | Rob Wheeler | 551 | 1960 | |
| 49 | Jorge Canales# | 551 | 1985 | |
| 49 | Félix Morán | 551 | 1914 | |
| 49 | William Evans | 551 | 1979 | |
| 49 | Jorge Ramírez# | 551 | 1988 | |
| 54 | Rubén Vega | 550 | 1969 | |
| 54 | John Watson | 550 | 1950 | |
| 54 | Román Padilla# | 550 | 1989 | |
| 54 | Corbett Ellis | 550 | 1916 | |
| 58 | Cristián Trujillo | 549 | 1951 | |
| 59 | Gunner Ashby | 548 | 1980 | |
| 60 | Randall Watson | 547 | 1963 | |
| 60 | Jared Hayes# | 547 | 1985 | |
| 62 | Mario Ruíz | 546 | 1978 | |
| 62 | Brendon Turner | 546 | 1937 | |
| 62 | Arturo Ramos | 546 | 1977 | |
| 62 | Mike Young | 546 | 1912 | |
| 62 | Jorge Alvarado | 546 | 1964 | |
| 67 | Valentín Aguilar | 544 | 1970 | |
| 67 | Joe Thompson | 544 | 1926 | |
| 67 | Dan Dethridge | 544 | 1936 | |
| 70 | Pete Raymond | 543 | 1975 | |
| 71 | Phil Carter | 542 | 1977 | |
| 71 | Eduardo Durán | 542 | 1921 | |
| 73 | Curt Cornett# | 541 | 1984 | |
| 73 | Roland Williamson | 541 | 1966 | |
| 73 | Ernie Stevenson | 541 | 1940 | |
| 76 | Juan Mora# | 540 | 1990 | |
| 77 | Ernest Snow | 539 | 1975 | |
| 77 | Sergio Berrios | 539 | 1935 | |
| 79 | Juan García | 538 | 1950 | |
| 79 | Richard Vaughn | 538 | 1936 | |
| 79 | Peter Bell | 538 | 1920 | |
| 79 | Chris Mathews | 538 | 1913 | |
| 79 | Víctor Navarro | 538 | 1957 | |
| 84 | Jake Cornett | 537 | 1970 | |
| 84 | Bernardo García | 537 | 1935 | |
| 84 | Eric Beard | 537 | 1920 | |
| 87 | Juan Pérez | 536 | 1945 | |
| 87 | William Evans | 536 | 1978 | |
| 87 | Jorge Alvarado | 536 | 1963 | |
| 87 | Josh Garrett | 536 | 1943 | |
| 91 | Roosevelt Nelson | 535 | 1947 | |
| 92 | Steven Powell# | 534 | 1979 | |
| 92 | Elmo Besson | 534 | 1919 | |
| 94 | Miguel Mejía | 533 | 1941 | |
| 94 | Mun-wah Shui | 533 | 1915 | |
| 94 | Don Doyle | 533 | 1934 | |
| 94 | Chris McCoy | 533 | 1915 | |
| 94 | Milo MacPherson# | 533 | 1980 | |
| 94 | Ernest Snow | 533 | 1977 | |
| 100 | Francisco Orellamo# | 532 | 1984 |
