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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Matt Wood | 50 | 1950-1953 | |
| 2 | Enrique Medine# | 43 | 1987-1990 | |
| 3 | Josh Thompson | 42 | 1959-1962 | |
| 4 | António Pérez | 41 | 1961-1964 | |
| 5 | José Sandoval | 40 | 1954-1957 | |
| 6 | Wake Odenbach# | 39 | 1984-1987 | |
| 6 | Quincy Wheeler | 39 | 1971-1974 | |
| 8 | Paul Jones# | 38 | 1978-1981 | |
| 8 | Nyles Lago# | 38 | 1976-1978 | |
| 8 | Patrick Sanderson | 38 | 1952-1955 | |
| 11 | Jonathan Rodgers | 37 | 1966-1969 | |
| 12 | Dan Bryant | 36 | 1955-1958 | |
| 13 | Carlos González | 35 | 1959-1962 | |
| 13 | Rich Hughes# | 35 | 1986-1989 | |
| 15 | George Barlow | 34 | 1942-1945 | |
| 15 | Bill Burnett# | 34 | 1984-1987 | |
| 15 | Colin Wilkins | 34 | 1954-1957 | |
| 18 | Grant Houck | 33 | 1973-1976 | |
| 18 | John Raymond | 33 | 1966-1969 | |
| 18 | António Sosa# | 33 | 1982-1985 | |
| 21 | James McDonald# | 32 | 1979-1982 | |
| 22 | Marc Holloway# | 31 | 1987-1990 | |
| 22 | Javier Salazar | 31 | 1950-1953 | |
| 24 | Troy Baker# | 30 | 1978-1981 | |
| 24 | Richard Robinson# | 30 | 1987-1990 | |
| 26 | Samuel Bramati | 29 | 1934-1937 | |
| 26 | Guillermo Cruz# | 29 | 1976-1979 | |
| 26 | George Wagner | 29 | 1956-1959 | |
| 29 | Eduardo Caprioglio# | 28 | 1976-1979 | |
| 29 | Nelson Davis | 28 | 1962-1965 | |
| 29 | Xavier Garza# | 28 | 1980-1983 | |
| 29 | Lodewijk Hawley | 28 | 1942-1945 | |
| 29 | Peter Marshall# | 28 | 1986-1989 | |
| 34 | Jack Burns | 27 | 1967-1971 | |
| 34 | Jerry Horton | 27 | 1976-1979 | |
| 34 | Mario Miranda | 27 | 1960-1963 | |
| 34 | Claudio Moreno | 27 | 1948-1951 | |
| 34 | Dave Swanson# | 27 | 1985-1988 | |
| 39 | Antonio Brekke# | 26 | 1987-1990 | |
| 39 | Geoffrey Clark | 26 | 1955-1958 | |
| 39 | Jim Craft# | 26 | 1985-1988 | |
| 39 | Melvin Erwin | 26 | 1967-1970 | |
| 39 | Steven Martin | 26 | 1968-1972 | |
| 39 | Joe Morgan | 26 | 1950-1953 | |
| 39 | Martin Trenholm# | 26 | 1984-1987 | |
| 46 | Joe Davis | 25 | 1938-1941 | |
| 46 | Joe Franklin# | 25 | 1987-1990 | |
| 46 | Fortunato Friuli# | 25 | 1984-1987 | |
| 46 | Joe Goodman | 25 | 1976-1979 | |
| 46 | Dale Jewell# | 25 | 1979-1982 | |
| 46 | Carlos Montero# | 25 | 1987-1990 | |
| 46 | Emílio Román | 25 | 1941-1944 | |
| 46 | Steve Ward# | 25 | 1980-1983 | |
| 54 | Vern Farriss | 24 | 1958-1961 | |
| 54 | Joe Martin | 24 | 1942-1945 | |
| 54 | Ray Meyers# | 24 | 1987-1990 | |
| 54 | Salvador Noriega | 24 | 1980-1983 | |
| 58 | José González | 23 | 1965-1968 | |
| 58 | Santiago Meléndez# | 23 | 1984-1987 | |
| 58 | Everett Sánchez# | 23 | 1982-1985 | |
| 58 | Dave Young | 23 | 1949-1952 | |
| 62 | Roberto Acosta# | 22 | 1984-1987 | |
| 62 | Michael Bacon# | 22 | 1976-1979 | |
| 62 | Sergio Durán | 22 | 1927-1930 | |
| 62 | Vincent Jarvis | 22 | 1955-1958 | |
| 62 | Felipe López | 22 | 1955-1958 | |
| 62 | Ed McCubbin | 22 | 1954-1957 | |
| 62 | Brian Thompson | 22 | 1963-1966 | |
| 62 | Phil Thompson | 22 | 1962-1965 | |
| 70 | José Chávez | 21 | 1939-1942 | |
| 70 | Pablo Contreras# | 21 | 1986-1989 | |
| 70 | George Crosby | 21 | 1965-1968 | |
| 70 | Erik Fisher | 21 | 1982-1985 | |
| 70 | Burt Franklin | 21 | 1961-1964 | |
| 70 | Dave Jordan# | 21 | 1980-1983 | |
| 70 | Sid Kimball# | 21 | 1984-1987 | |
| 70 | Gil LeMond# | 21 | 1976-1979 | |
| 70 | Xavier Martínez | 21 | 1947-1950 | |
| 70 | Ryan Maynard# | 21 | 1981-1984 | |
| 70 | José Ortíz | 21 | 1943-1946 | |
| 70 | Julián Salazar | 21 | 1927-1930 | |
| 70 | Julián Vega# | 21 | 1989-1991 | |
| 83 | Brady Allen | 20 | 1938-1941 | |
| 83 | Emílio Córdova# | 20 | 1976-1979 | |
| 83 | Ricardo Costello# | 20 | 1988-1991 | |
| 83 | Lee Fenton | 20 | 1965-1968 | |
| 83 | Alejandro Hernández | 20 | 1946-1949 | |
| 83 | Claudio Marín | 20 | 1938-1941 | |
| 83 | Kurt Milligan | 20 | 1957-1960 | |
| 83 | Ted Price | 20 | 1957-1960 | |
| 83 | Mario Toro | 20 | 1935-1938 | |
| 92 | Germán Castaneda# | 19 | 1983-1986 | |
| 92 | Richard Coleman# | 19 | 1988-1991 | |
| 92 | Ramón Fargas | 19 | 1967-1970 | |
| 92 | Bryan Galló | 19 | 1973-1976 | |
| 92 | Wilber Hill# | 19 | 1980-1983 | |
| 92 | Jamie Jones | 19 | 1938-1941 | |
| 92 | Roberto Murillo | 19 | 1933-1936 | |
| 92 | Eduardo Ojeda# | 19 | 1985-1988 | |
| 92 | Jesús Rodríguez# | 19 | 1976-1979 |
