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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | IP | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Jake Acevedo | 378 | 1948 | |
| 2 | Bartolo Silva | 374 | 1948 | |
| 3 | Joaquín Márquez# | 371 | 1980 | |
| 4 | Pedro Garza | 370 | 1952 | |
| 5 | Phil McKnight# | 369 | 1986 | |
| 6 | Stan Ivey# | 367 | 1979 | |
| 6 | Jorge Colón | 367 | 1914 | |
| 8 | Pedro Ramos# | 365 | 1977 | |
| 8 | Rex Baldwin | 365 | 1967 | |
| 10 | Carlos Gallegos# | 364 | 1989 | |
| 10 | Jorge Colón | 364 | 1913 | |
| 10 | Rick Steward | 364 | 1950 | |
| 10 | Bartolo Gómez | 364 | 1977 | |
| 14 | Henri Rospigliosi | 363 | 1948 | |
| 14 | Kevin Spencer | 363 | 1917 | |
| 14 | David Marino | 363 | 1950 | |
| 17 | Ed Moore | 362 | 1964 | |
| 17 | Gregg Morgan | 362 | 1971 | |
| 17 | Juan Sánchez | 362 | 1950 | |
| 20 | Juan Quiñonez | 361 | 1939 | |
| 20 | Vincent Denton# | 361 | 1982 | |
| 22 | Manny Márquez | 360 | 1954 | |
| 22 | John Mosley# | 360 | 1977 | |
| 22 | Doug Reed# | 360 | 1988 | |
| 25 | Carl Kelley# | 359 | 1985 | |
| 25 | Rob Craig# | 359 | 1991 | |
| 25 | Pedro Ramos# | 359 | 1978 | |
| 28 | Bento Cotimo | 358 | 1955 | |
| 28 | Teok-kyu On* | 358 | 1920 | |
| 28 | Roy Kline | 358 | 1974 | |
| 28 | Lopes Falagueiro | 358 | 1948 | |
| 28 | Salvador Cuellar | 358 | 1953 | |
| 28 | Rick Steward | 358 | 1951 | |
| 28 | Lufti bin Jubair | 358 | 1912 | |
| 35 | Mark Richardson | 357 | 1950 | |
| 35 | David Leonard# | 357 | 1985 | |
| 37 | Charles Hutcheson# | 356 | 1986 | |
| 37 | Phil McKnight# | 356 | 1987 | |
| 37 | Craig Rollins# | 356 | 1984 | |
| 37 | Felipe Rosales | 356 | 1961 | |
| 37 | Ralph Gordon | 356 | 1945 | |
| 37 | Mauro Machado | 356 | 1946 | |
| 37 | Arthur Pierce | 356 | 1945 | |
| 37 | Ken Benton | 356 | 1972 | |
| 37 | Julián Rea | 356 | 1961 | |
| 37 | Bento Cotimo | 356 | 1954 | |
| 47 | Rick Steward | 355 | 1952 | |
| 47 | Rick Steward | 355 | 1953 | |
| 47 | Alejandro Reyes# | 355 | 1987 | |
| 47 | Jake Harvey# | 355 | 1984 | |
| 47 | Harry Stewart | 355 | 1970 | |
| 47 | Francisco González* | 355 | 1917 | |
| 47 | Mark Richardson | 355 | 1951 | |
| 54 | John Daniels | 354 | 1964 | |
| 54 | Juan Valadez | 354 | 1964 | |
| 54 | Vincent Denton# | 354 | 1980 | |
| 54 | Ricardo González | 354 | 1915 | |
| 54 | Jesse Monroe | 354 | 1959 | |
| 54 | Rex Baldwin | 354 | 1966 | |
| 54 | Pedro Ramos# | 354 | 1976 | |
| 54 | Abel Love# | 354 | 1989 | |
| 54 | Juan Ortíz | 354 | 1946 | |
| 63 | Carlos Gallegos# | 353 | 1988 | |
| 63 | Bret Johnson# | 353 | 1989 | |
| 63 | John Mitchell | 353 | 1962 | |
| 63 | Doug Reed# | 353 | 1991 | |
| 63 | Richard Rowland | 353 | 1946 | |
| 63 | Nick Willerton# | 353 | 1987 | |
| 63 | Kyung-hyun Yang# | 353 | 1977 | |
| 70 | Paul Palmer# | 352 | 1991 | |
| 70 | José Rosales | 352 | 1952 | |
| 70 | Vicente López | 352 | 1961 | |
| 70 | Carlos González# | 352 | 1981 | |
| 70 | David Marino | 352 | 1952 | |
| 70 | Dan Cunningham# | 352 | 1983 | |
| 70 | Jorge López | 352 | 1973 | |
| 70 | Marvin Arrington# | 352 | 1986 | |
| 70 | Charles Smith# | 352 | 1988 | |
| 70 | Bento Cotimo | 352 | 1956 | |
| 70 | Dale Lord | 352 | 1973 | |
| 81 | Randall Hatcher | 351 | 1948 | |
| 81 | Ryan Watson# | 351 | 1973 | |
| 81 | Bob Vann# | 351 | 1981 | |
| 81 | Ed Boyd | 351 | 1954 | |
| 81 | José Sánchez | 351 | 1964 | |
| 81 | Rodrigo Herrera# | 351 | 1987 | |
| 81 | Dan Cunningham# | 351 | 1984 | |
| 81 | Clarence Lloyd | 351 | 1957 | |
| 89 | Germán Taváres | 350 | 1940 | |
| 89 | Tim Hall | 350 | 1923 | |
| 89 | José Barrera | 350 | 1952 | |
| 89 | José Hernández | 350 | 1935 | |
| 89 | Víctor Toledo | 350 | 1976 | |
| 89 | Salvador Cuellar | 350 | 1952 | |
| 95 | Armando Mendoza | 349 | 1968 | |
| 95 | Keith Taylor | 349 | 1961 | |
| 95 | Oliver Erwin | 349 | 1941 | |
| 95 | Artie Hess | 349 | 1973 | |
| 95 | José Barrera | 349 | 1950 | |
| 100 | Ricardo Sierra# | 348 | 1985 |
