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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Francisco Díaz | 141 | 1912-1916 | |
| 2 | Clayton Gray | 101 | 1913-1917 | |
| 3 | David Cheslin | 100 | 1912-1914 | |
| 4 | Jerry Thompson | 98 | 1912-1916 | |
| 5 | Eddie Brandt | 96 | 1966-1974 | |
| 6 | Gilberto Cruz | 91 | 1975-1983 | |
| 7 | Kevin Ferris | 87 | 1911-1915 | |
| 8 | Jeff Thomas | 86 | 1983-1990 | |
| 9 | Jeff Davis | 84 | 1912-1916 | |
| 9 | Marcos Sánchez | 84 | 1914-1917 | |
| 11 | John McBride | 83 | 1913-1918 | |
| 12 | Denny Daugherty | 82 | 1975-1983 | |
| 13 | Li-xue Wang | 81 | 1966-1969 | |
| 14 | Jesús Martínez | 78 | 1956-1962 | |
| 15 | Willie Harbin | 77 | 1914-1917 | |
| 16 | Clay Anderson | 75 | 1956-1961 | |
| 16 | Xavier López | 75 | 1953-1955 | |
| 18 | David Moore | 73 | 1913-1918 | |
| 19 | Bob Corbin | 72 | 1966-1969 | |
| 20 | Mark Seymour# | 71 | 1982-1991 | |
| 21 | Carlos Alomar# | 70 | 1975-1989 | |
| 21 | Byron Ford | 70 | 1978-1985 | |
| 21 | Vincente Rivas | 70 | 1913-1916 | |
| 21 | Teruo Takata | 70 | 1950-1955 | |
| 25 | Michael Halliburton | 69 | 1915-1916 | |
| 25 | Joe Pérez# | 69 | 1982-1989 | |
| 27 | Rob Dickson | 67 | 1975-1977 | |
| 27 | Matt Logan | 67 | 1975-1979 | |
| 27 | Jason McDonald | 67 | 1911-1917 | |
| 27 | Valentín Souza# | 67 | 1984-1988 | |
| 31 | Monte Brando | 65 | 1967-1977 | |
| 31 | Sergio López# | 65 | 1985-1990 | |
| 31 | Dylan MacHendrie | 65 | 1911-1917 | |
| 34 | Danny Lyttle | 64 | 1948-1952 | |
| 34 | Shawn Wagner | 64 | 1911-1915 | |
| 36 | Micah Bolitho# | 63 | 1988-1989 | |
| 36 | Ted Webb | 63 | 1911-1914 | |
| 38 | Alex Hammond | 62 | 1913-1926 | |
| 38 | Zachary King | 62 | 1911-1915 | |
| 38 | Joshua McGrath# | 62 | 1983-1989 | |
| 41 | Roy Buschlen | 61 | 1960-1964 | |
| 41 | José Gonzáles | 61 | 1957-1961 | |
| 41 | Vincent Heath | 61 | 1955-1963 | |
| 44 | Romeo Brancati | 60 | 1960-1965 | |
| 44 | Jerry Gore | 60 | 1977-1985 | |
| 44 | Raúl Navarro | 60 | 1916-1926 | |
| 44 | Jorge Ramírez# | 60 | 1989-1991 | |
| 48 | Gray Akerval | 59 | 1967-1974 | |
| 48 | Bialy Bartnik | 59 | 1967-1970 | |
| 48 | Bryant Thomas | 59 | 1945-1953 | |
| 48 | Doug Thompson | 59 | 1956-1965 | |
| 48 | Juan Vázquez# | 59 | 1984-1991 | |
| 53 | Russell Abbott | 58 | 1958-1963 | |
| 53 | Sergio Berrios | 58 | 1937-1941 | |
| 53 | Casey Boyd | 58 | 1911-1914 | |
| 53 | Gary Hubbard | 58 | 1957-1962 | |
| 57 | Carlos Guthrie | 57 | 1913-1917 | |
| 57 | Ronnie Moore | 57 | 1911-1916 | |
| 59 | Sergio Acevedo | 56 | 1963-1967 | |
| 59 | Raúl Ayers | 56 | 1957-1963 | |
| 59 | Isaac Love | 56 | 1959-1963 | |
| 59 | Carlos Luna | 56 | 1911-1914 | |
| 63 | Hunter Dominey | 55 | 1976-1987 | |
| 63 | Juan García | 55 | 1977-1987 | |
| 63 | Gustavo Ortega | 55 | 1939-1949 | |
| 63 | Julien Rey | 55 | 1915-1920 | |
| 63 | Bastien Sanguinacco# | 55 | 1985-1986 | |
| 63 | Marvin Savage | 55 | 1967-1969 | |
| 63 | Dave Tucker | 55 | 1960-1965 | |
| 70 | Jorge López | 54 | 1979-1989 | |
| 70 | James McDonald# | 54 | 1985-1989 | |
| 70 | Shigeaki Mochizuki# | 54 | 1986-1989 | |
| 70 | Dave Parker | 54 | 1938-1949 | |
| 74 | Joe Hickman | 53 | 1967-1975 | |
| 74 | Eddie Webber | 53 | 1957-1963 | |
| 76 | Theodore Jensen | 52 | 1954-1956 | |
| 76 | Ronnie Moore | 52 | 1950-1956 | |
| 76 | Juan Peralta | 52 | 1983-1989 | |
| 76 | José Rivera | 52 | 1915-1919 | |
| 76 | Scott Wilson | 52 | 1912-1915 | |
| 81 | Paco Aragón# | 51 | 1981-1988 | |
| 81 | Luis Gómez# | 51 | 1975-1991 | |
| 81 | Masashige Takayama | 51 | 1945-1949 | |
| 84 | Justin Bass# | 50 | 1980-1982 | |
| 84 | Cristián García | 50 | 1925-1929 | |
| 84 | Roldão Glria# | 50 | 1986-1991 | |
| 84 | Yifter Olushegun | 50 | 1976-1987 | |
| 84 | Stan Rainey | 50 | 1911-1916 | |
| 84 | Felipe Sandoval# | 50 | 1987-1991 | |
| 90 | Jack Martin | 49 | 1962-1963 | |
| 90 | Patrick Sanderson | 49 | 1959-1962 | |
| 90 | Juan Trevino | 49 | 1912-1915 | |
| 90 | Adrian Walcott | 49 | 1958-1974 | |
| 90 | Dan Walls | 49 | 1975-1984 | |
| 95 | Iwane Agano | 48 | 1954-1955 | |
| 95 | Roberto Aponte# | 48 | 1982-1990 | |
| 95 | Gabriel Hernández | 48 | 1914-1917 | |
| 95 | Stan Joyce# | 48 | 1982-1987 | |
| 95 | George Ladner | 48 | 1974-1982 | |
| 95 | Ben O'Connor | 48 | 1911-1915 |
