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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Jeff Thomas | 63 | 1983-1990 | |
| 2 | Carlos Alomar# | 50 | 1975-1989 | |
| 3 | Gabriel Hernández | 48 | 1914-1917 | |
| 4 | Romeo Brancati | 47 | 1960-1965 | |
| 5 | Denny Daugherty | 45 | 1975-1983 | |
| 6 | Paco Chávez | 40 | 1912-1916 | |
| 6 | Daniel Gonzáles# | 40 | 1979-1989 | |
| 8 | Brian Thomas | 36 | 1915-1916 | |
| 9 | Diego Hernández# | 33 | 1982-1988 | |
| 9 | Lawrence Jenkins# | 33 | 1986-1990 | |
| 11 | Ken Heard | 32 | 1911-1919 | |
| 12 | Edward Thomas# | 31 | 1985-1987 | |
| 13 | Feitze Heijnen | 30 | 1934-1939 | |
| 14 | Paulino Cora | 29 | 1911-1911 | |
| 14 | Iván Reynoso | 29 | 1945-1947 | |
| 14 | Sergio Sousa# | 29 | 1978-1989 | |
| 17 | Chad Scott | 28 | 1964-1965 | |
| 18 | Pedro Andrade | 27 | 1959-1969 | |
| 18 | Rubén Ortíz | 27 | 1953-1957 | |
| 20 | Rick Christian | 26 | 1912-1913 | |
| 21 | Benedicto Castillo | 25 | 1980-1987 | |
| 21 | Enrique Costello | 25 | 1961-1963 | |
| 21 | Alfredo González | 25 | 1928-1931 | |
| 21 | Joaquín Muñíz# | 25 | 1981-1984 | |
| 25 | Ellis Brown | 24 | 1977-1984 | |
| 25 | Ben O'Connor | 24 | 1911-1915 | |
| 25 | José Palmeiro# | 24 | 1979-1989 | |
| 25 | Yasutake Tomita | 24 | 1975-1977 | |
| 29 | Allen David | 23 | 1956-1958 | |
| 29 | Richard Hicks | 23 | 1975-1978 | |
| 29 | Cisco Medina# | 23 | 1985-1986 | |
| 29 | Jorge Miranda | 23 | 1956-1961 | |
| 29 | Melvin Potts | 23 | 1916-1929 | |
| 29 | Norberto Rodríguez | 23 | 1912-1913 | |
| 35 | Bartolo Aleixa | 22 | 1950-1954 | |
| 35 | Eddie Brandt | 22 | 1966-1974 | |
| 35 | Tim Cox | 22 | 1957-1961 | |
| 35 | Jaime Díaz | 22 | 1952-1953 | |
| 35 | Damiano Fiacconi | 22 | 1964-1965 | |
| 35 | Leland McDowell# | 22 | 1981-1985 | |
| 35 | Denis van Barneveld# | 22 | 1984-1990 | |
| 35 | Darren Washington | 22 | 1911-1912 | |
| 43 | Dave Gibson | 21 | 1911-1913 | |
| 43 | Thibault Jarry | 21 | 1936-1943 | |
| 43 | Sam Moore | 21 | 1916-1917 | |
| 43 | Ramón Ortíz | 21 | 1973-1976 | |
| 43 | Salvador Pineda | 21 | 1963-1964 | |
| 43 | Ron Roy | 21 | 1966-1970 | |
| 43 | Raúl Valenzuela | 21 | 1936-1939 | |
| 43 | Loren Walters | 21 | 1981-1987 | |
| 51 | Jeff Davis | 20 | 1912-1916 | |
| 51 | Peter Deakin | 20 | 1975-1978 | |
| 51 | Floyd Duff | 20 | 1975-1975 | |
| 51 | Pancho Gómez | 20 | 1955-1956 | |
| 51 | Randy Heap | 20 | 1948-1949 | |
| 51 | Woodrow Lee | 20 | 1911-1915 | |
| 51 | Warren Simpson# | 20 | 1984-1984 | |
| 51 | Al Wyatt | 20 | 1913-1913 | |
| 59 | José Carlos Díaz | 19 | 1979-1988 | |
| 59 | Adrian Gamble | 19 | 1932-1935 | |
| 59 | Robinson García | 19 | 1934-1937 | |
| 59 | Álex Gil | 19 | 1948-1949 | |
| 59 | Pepe Ledezma | 19 | 1919-1923 | |
| 59 | Héctor Mendoza | 19 | 1963-1970 | |
| 59 | Henry O'Toole | 19 | 1912-1921 | |
| 59 | Dan Pratt | 19 | 1917-1919 | |
| 59 | Ron Swallow# | 19 | 1975-1976 | |
| 68 | Albert Bernal | 18 | 1966-1969 | |
| 68 | Roberto Cantú | 18 | 1958-1963 | |
| 68 | Ken Lawson | 18 | 1914-1921 | |
| 68 | Richie Newhouse | 18 | 1948-1952 | |
| 68 | Russ Phipps | 18 | 1949-1952 | |
| 68 | Diego Torres# | 18 | 1985-1991 | |
| 74 | Khayyat bin Khalid | 17 | 1977-1985 | |
| 74 | Derek Blankenship | 17 | 1970-1975 | |
| 74 | Vincent Carpentier | 17 | 1947-1950 | |
| 74 | Alfredo Cortéz# | 17 | 1986-1986 | |
| 74 | George Fox | 17 | 1952-1952 | |
| 74 | Joe King | 17 | 1917-1917 | |
| 74 | Lou Miner | 17 | 1911-1913 | |
| 74 | Tom Odom | 17 | 1911-1914 | |
| 74 | Kevin Porter# | 17 | 1984-1987 | |
| 74 | John Smith | 17 | 1916-1922 | |
| 84 | Len Fanner# | 16 | 1989-1990 | |
| 84 | Ambrose Foust | 16 | 1976-1978 | |
| 84 | Fernando Hernández | 16 | 1915-1915 | |
| 84 | Derek Hutchings | 16 | 1985-1985 | |
| 84 | Ray Parker# | 16 | 1976-1988 | |
| 84 | Gregorio Pierotti | 16 | 1958-1959 | |
| 84 | Jesús Ramírez# | 16 | 1981-1990 | |
| 84 | Michael Robinson | 16 | 1984-1989 | |
| 84 | Nathan Russell | 16 | 1912-1917 | |
| 84 | Karl Schmidt | 16 | 1963-1965 | |
| 84 | Juan Jose Torrez | 16 | 1982-1990 | |
| 84 | Jian Wang | 16 | 1948-1955 | |
| 84 | Ron White | 16 | 1911-1915 | |
| 84 | Scott Wilson | 16 | 1912-1915 | |
| 98 | Cory Caldicott | 15 | 1966-1970 | |
| 98 | Gustavo Hernández | 15 | 1930-1931 | |
| 98 | Tomás Nava | 15 | 1988-1989 |
