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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Micah Bolitho# | 63 | 1988-1989 | |
| 2 | Carlos Guthrie | 57 | 1913-1917 | |
| 3 | Isaac Love | 56 | 1959-1963 | |
| 4 | Marcos Sánchez | 54 | 1914-1917 | |
| 5 | Cristián García | 50 | 1925-1929 | |
| 5 | Felipe Sandoval# | 50 | 1987-1991 | |
| 7 | Juan Trevino | 49 | 1912-1915 | |
| 8 | Hunter Dominey | 47 | 1976-1987 | |
| 9 | Ian Grooms# | 45 | 1977-1980 | |
| 10 | Gary Hubbard | 43 | 1957-1962 | |
| 11 | Luis Gómez# | 42 | 1975-1991 | |
| 11 | Francisco Romero# | 42 | 1985-1988 | |
| 13 | José Medrano | 39 | 1951-1952 | |
| 13 | Esteban Torres | 39 | 1914-1915 | |
| 15 | Millard Arnold | 38 | 1978-1987 | |
| 15 | Don Hudson | 38 | 1913-1918 | |
| 17 | Ethan Opie | 37 | 1959-1965 | |
| 17 | Lou Stephens | 37 | 1957-1961 | |
| 19 | Mack Duncan | 36 | 1911-1919 | |
| 19 | Casper Versaal | 36 | 1949-1954 | |
| 21 | Bill Gordon# | 34 | 1988-1990 | |
| 21 | Danny Warren | 34 | 1934-1941 | |
| 23 | Nick Boone | 33 | 1912-1915 | |
| 23 | Conan Mercer | 33 | 1912-1916 | |
| 23 | Álvaro Ortíz | 33 | 1951-1954 | |
| 23 | Ben Woods | 33 | 1959-1962 | |
| 27 | Drake Day# | 31 | 1980-1982 | |
| 28 | Jeff Cherry# | 30 | 1982-1983 | |
| 28 | Jerry Gore | 30 | 1977-1985 | |
| 28 | Stan Joyce# | 30 | 1982-1987 | |
| 28 | Rick Ríos | 30 | 1980-1984 | |
| 28 | Will Ruíz | 30 | 1984-1984 | |
| 33 | Eric Crum | 29 | 1911-1912 | |
| 33 | Diego Hernández | 29 | 1922-1923 | |
| 33 | Kazunori Matsumoto | 29 | 1917-1925 | |
| 33 | Javier Silva# | 29 | 1987-1991 | |
| 33 | Alfredo Vega | 29 | 1979-1990 | |
| 38 | Broderick Knowles# | 28 | 1989-1991 | |
| 38 | Juan Pérez# | 28 | 1982-1984 | |
| 40 | Danny Lyttle | 27 | 1948-1952 | |
| 41 | Francisco Alston# | 26 | 1983-1986 | |
| 41 | Jason McDonald | 26 | 1911-1917 | |
| 41 | Manny Pérez | 26 | 1977-1989 | |
| 41 | Jaime Ramírez | 26 | 1983-1985 | |
| 41 | César Tobías | 26 | 1933-1937 | |
| 46 | Francisco Gutiérrez | 25 | 1948-1949 | |
| 46 | José Medina | 25 | 1952-1955 | |
| 46 | Roberto Medina | 25 | 1975-1980 | |
| 46 | Mark Nelson | 25 | 1975-1976 | |
| 50 | Pacu Djapic | 24 | 1912-1918 | |
| 50 | Chris Johnson | 24 | 1975-1978 | |
| 50 | Fred Lewis | 24 | 1914-1916 | |
| 50 | Jack Nicholas | 24 | 1975-1978 | |
| 50 | Craig Peters | 24 | 1912-1917 | |
| 50 | Augusto Rea# | 24 | 1977-1990 | |
| 50 | Jeff Snyder | 24 | 1945-1949 | |
| 50 | Teruo Takata | 24 | 1950-1955 | |
| 50 | Chad Thompson# | 24 | 1985-1987 | |
| 59 | Darren Morgenstern# | 23 | 1982-1984 | |
| 59 | Alfonso Rivera# | 23 | 1980-1991 | |
| 59 | Chuck Watson | 23 | 1964-1965 | |
| 62 | Matt Armstrong | 22 | 1911-1912 | |
| 62 | Mack Morris | 22 | 1964-1975 | |
| 62 | Ed Reynolds | 22 | 1913-1920 | |
| 65 | Cristián Betancourt | 21 | 1966-1971 | |
| 65 | Carlos Hernández# | 21 | 1986-1989 | |
| 65 | Hugh Peck | 21 | 1916-1917 | |
| 65 | Alejandro Sánchez | 21 | 1957-1957 | |
| 69 | Iván Cruz | 20 | 1917-1921 | |
| 69 | Iván Padilla | 20 | 1954-1955 | |
| 69 | Kent Rodríguez | 20 | 1939-1940 | |
| 69 | Júlio Soto | 20 | 1950-1952 | |
| 73 | Eric Beard | 19 | 1924-1926 | |
| 73 | Chris Cooper | 19 | 1926-1930 | |
| 73 | Tomás Cruz | 19 | 1965-1968 | |
| 73 | Bill Delaney | 19 | 1942-1953 | |
| 73 | Carlos Flores | 19 | 1970-1973 | |
| 73 | Dylan MacHendrie | 19 | 1911-1917 | |
| 73 | Kanne Oostenbroek | 19 | 1916-1919 | |
| 80 | Joseph Battams# | 18 | 1988-1988 | |
| 80 | Ricardo Ferreira | 18 | 1939-1949 | |
| 80 | Manuel Figueroa | 18 | 1975-1989 | |
| 80 | Ismael Gamboa | 18 | 1950-1951 | |
| 80 | Roberto Gómes | 18 | 1917-1920 | |
| 80 | Adrián Guerrero | 18 | 1951-1952 | |
| 80 | Rafael Guerrero | 18 | 1967-1968 | |
| 80 | Gerardo Rivera# | 18 | 1983-1985 | |
| 80 | Dave Roy | 18 | 1917-1922 | |
| 80 | Cal Sampson | 18 | 1974-1983 | |
| 80 | Herb Walters | 18 | 1935-1936 | |
| 80 | Bob Warren# | 18 | 1975-1978 | |
| 80 | Wallace Welch | 18 | 1959-1963 | |
| 93 | Armando Alvarado | 17 | 1955-1957 | |
| 93 | Lorenzo Ayala | 17 | 1965-1965 | |
| 93 | Roberto Baudin | 17 | 1963-1969 | |
| 93 | Bob Browne# | 17 | 1982-1985 | |
| 93 | Cris Castro | 17 | 1970-1977 | |
| 93 | Larry McCarthy | 17 | 1922-1923 | |
| 93 | Jorge Morán | 17 | 1942-1953 | |
| 93 | Nate Morrison# | 17 | 1983-1986 |
