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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Héctor Valdéz | 201 | 1932-1940 | |
| 2 | Bobby Meyers | 168 | 1936-1941 | |
| 3 | Leonardo Zamora | 166 | 1949-1953 | |
| 4 | Tom Krause | 155 | 1911-1916 | |
| 5 | Todd Butler | 143 | 1911-1917 | |
| 5 | Barney Sherman | 143 | 1958-1965 | |
| 7 | Luis Guillén | 141 | 1975-1980 | |
| 8 | Tommy Davis | 139 | 1967-1974 | |
| 9 | Octávio Luna | 138 | 1981-1989 | |
| 10 | Jasper Willis | 133 | 1948-1952 | |
| 11 | Rafael Ortíz | 131 | 1911-1918 | |
| 12 | Kevin Engler | 127 | 1912-1916 | |
| 13 | Kensaku Harada | 126 | 1975-1979 | |
| 13 | Brad Lew | 126 | 1935-1941 | |
| 15 | César Valle# | 124 | 1977-1991 | |
| 16 | Kirby Walters | 123 | 1932-1937 | |
| 17 | Ernesto Caboverde | 121 | 1952-1955 | |
| 18 | Pedro Lugo | 118 | 1958-1963 | |
| 19 | Roberto Valenzuela | 116 | 1975-1984 | |
| 20 | Gahiji Apio | 115 | 1977-1987 | |
| 21 | Allen Haynes | 112 | 1978-1981 | |
| 22 | Dave Sedgwick | 111 | 1911-1915 | |
| 23 | Ernesto Durango | 109 | 1911-1915 | |
| 24 | Roberto Luna# | 107 | 1982-1991 | |
| 25 | Jorge Martínez | 106 | 1953-1957 | |
| 26 | Alexander DeYoung | 105 | 1936-1943 | |
| 26 | David Valle | 105 | 1958-1963 | |
| 28 | Nick English | 104 | 1962-1971 | |
| 28 | Orlando García | 104 | 1938-1948 | |
| 30 | Juan Macías | 103 | 1930-1933 | |
| 30 | Joe Morgan | 103 | 1911-1914 | |
| 32 | Jonah Clark | 102 | 1912-1914 | |
| 32 | Kieron Oppy | 102 | 1912-1915 | |
| 34 | Raúl Hernández | 101 | 1938-1940 | |
| 35 | Cliff Russell | 100 | 1914-1917 | |
| 35 | Khalil Sajid | 100 | 1976-1979 | |
| 37 | Yifter Kitwana | 99 | 1976-1979 | |
| 38 | Tim Spence | 98 | 1946-1949 | |
| 39 | Duane Stewart | 97 | 1974-1982 | |
| 40 | Santiago Rosa | 95 | 1911-1913 | |
| 40 | Ernesto Salto | 95 | 1916-1917 | |
| 42 | Jack Ashley | 94 | 1963-1971 | |
| 43 | Jerome Broadley | 93 | 1946-1955 | |
| 43 | Jimmy Lamb | 93 | 1940-1948 | |
| 43 | José Pérez | 93 | 1928-1931 | |
| 46 | Jimmy Parker | 92 | 1979-1985 | |
| 46 | Cliff Spronk | 92 | 1958-1961 | |
| 48 | Jim Lyons | 89 | 1967-1973 | |
| 49 | Loflinger Arrau | 88 | 1934-1939 | |
| 49 | António López | 88 | 1932-1935 | |
| 51 | Manuel González | 87 | 1974-1981 | |
| 51 | John Lurte | 87 | 1950-1951 | |
| 53 | Kent Marriott | 86 | 1940-1945 | |
| 54 | Gidde Brusselaars | 85 | 1977-1982 | |
| 54 | Joe Dean | 85 | 1951-1955 | |
| 54 | Francisco Espinoza | 85 | 1938-1941 | |
| 54 | Hector Guerrieri | 85 | 1974-1980 | |
| 54 | Jeremy Whitehead | 85 | 1961-1974 | |
| 59 | Edgardo Ortíz | 84 | 1974-1990 | |
| 60 | Tom Reeves# | 83 | 1985-1991 | |
| 60 | Rafael Rivera | 83 | 1966-1969 | |
| 62 | Keith Hayes | 82 | 1938-1941 | |
| 62 | Antonino Sarretti | 82 | 1930-1933 | |
| 64 | Francisco Mercado | 81 | 1975-1983 | |
| 64 | Craig Porter | 81 | 1939-1942 | |
| 66 | Giustiniano Gioberti# | 80 | 1984-1987 | |
| 66 | Alejandro Ramírez | 80 | 1935-1939 | |
| 68 | Carlos Díaz | 79 | 1951-1954 | |
| 69 | Javier Balderas | 77 | 1961-1974 | |
| 69 | Manuel Delgado | 77 | 1975-1979 | |
| 69 | Stephen Ducker | 77 | 1948-1953 | |
| 69 | Gerald Henry | 77 | 1961-1963 | |
| 69 | Andy Johnson | 77 | 1954-1955 | |
| 69 | Ramón Martínez | 77 | 1938-1940 | |
| 69 | Terry Ward | 77 | 1913-1914 | |
| 76 | Gilles Bernard | 76 | 1986-1990 | |
| 76 | Guillermo Pérez | 76 | 1975-1977 | |
| 76 | Tony Price | 76 | 1921-1924 | |
| 76 | Mathew Ward | 76 | 1914-1915 | |
| 80 | Gilberto Chávez | 75 | 1970-1976 | |
| 80 | Plácido Gutiérrez | 75 | 1955-1961 | |
| 80 | John Sexton | 75 | 1965-1969 | |
| 80 | Brian Spencer | 75 | 1944-1949 | |
| 84 | Miguel Angel Gutiérrez | 74 | 1970-1988 | |
| 84 | Eddie Kelm | 74 | 1940-1945 | |
| 84 | Tomás Morales | 74 | 1958-1961 | |
| 84 | Geunhye Pak | 74 | 1951-1957 | |
| 84 | Alfonso Pérez# | 74 | 1976-1991 | |
| 84 | Dan Williams | 74 | 1912-1915 | |
| 90 | Bob Fish | 73 | 1971-1989 | |
| 90 | Ricardo Greene | 73 | 1955-1960 | |
| 90 | Ken James | 73 | 1973-1977 | |
| 90 | Bertrand Mayne | 73 | 1913-1915 | |
| 90 | Lee Smith | 73 | 1982-1987 | |
| 90 | Roger Thompson | 73 | 1916-1917 | |
| 96 | Doug Hamilton | 72 | 1966-1972 | |
| 96 | Jorge Hernández | 72 | 1955-1961 | |
| 96 | Luis Hernández | 72 | 1953-1956 | |
| 96 | Diego Ramírez | 72 | 1973-1977 | |
| 96 | Tony Segura | 72 | 1957-1965 |
