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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Juan García | 104 | 1976-1989 | |
| 2 | Zach Rice | 81 | 1977-1988 | |
| 3 | Jason O'Mackesey | 77 | 1957-1960 | |
| 4 | Rusty Simon | 76 | 1958-1963 | |
| 5 | Alex Shepherd | 69 | 1966-1969 | |
| 6 | Mario Rosa | 58 | 1912-1921 | |
| 7 | Bailey Watkinson# | 46 | 1984-1985 | |
| 8 | Gene Davis | 45 | 1954-1956 | |
| 9 | Claudio Torres | 44 | 1967-1974 | |
| 10 | Gero Hiemer | 43 | 1928-1932 | |
| 11 | Adrián Romero | 42 | 1957-1961 | |
| 12 | Francisco López | 41 | 1966-1975 | |
| 12 | Gary Nelson | 41 | 1965-1967 | |
| 14 | Mike Kline | 40 | 1945-1947 | |
| 15 | Conner Roberts | 39 | 1975-1979 | |
| 16 | Alfredo Gusmán | 38 | 1978-1989 | |
| 16 | Kevin Hansen | 38 | 1946-1949 | |
| 16 | Jesús Torres | 38 | 1950-1958 | |
| 19 | John King# | 37 | 1983-1991 | |
| 19 | Jeff Taylor | 37 | 1966-1970 | |
| 21 | Javier Acosta | 36 | 1971-1973 | |
| 21 | Philip Grimes | 36 | 1913-1916 | |
| 23 | Brody Kelly | 35 | 1969-1973 | |
| 23 | Nathan Martin | 35 | 1973-1975 | |
| 23 | Jay Polanco | 35 | 1978-1981 | |
| 26 | Jason Fowler | 34 | 1958-1959 | |
| 26 | Clayton Gray | 34 | 1912-1913 | |
| 26 | Carlos Merced# | 34 | 1987-1989 | |
| 29 | Mario Santos | 33 | 1974-1975 | |
| 30 | John Eckard | 32 | 1978-1984 | |
| 30 | John Morgan | 32 | 1970-1974 | |
| 30 | Darge Mwendapole | 32 | 1951-1951 | |
| 33 | Cristián Andrés | 31 | 1935-1937 | |
| 34 | Leonilde Bach | 30 | 1977-1988 | |
| 34 | Sandy Cuevas | 30 | 1942-1946 | |
| 34 | Fyodor Daniev | 30 | 1963-1968 | |
| 34 | Luis Gil# | 30 | 1984-1985 | |
| 34 | Ron von Lahr | 30 | 1969-1975 | |
| 39 | Arthur Gray# | 29 | 1984-1988 | |
| 39 | Mark Kerr | 29 | 1961-1963 | |
| 39 | Duane Thompson | 29 | 1937-1940 | |
| 42 | Jason Corbin | 28 | 1911-1916 | |
| 42 | Arturo Longoria | 28 | 1973-1976 | |
| 42 | Juan Sosa | 28 | 1963-1964 | |
| 45 | Bernardo Carrión | 27 | 1982-1987 | |
| 45 | Jake Hicks | 27 | 1936-1941 | |
| 45 | Austin Johnson | 27 | 1955-1956 | |
| 45 | Scott Kennedy | 27 | 1915-1919 | |
| 45 | Garrick Kitley | 27 | 1916-1917 | |
| 45 | Roy Lee | 27 | 1960-1965 | |
| 45 | Mike Powell# | 27 | 1989-1990 | |
| 45 | Jim Richardson | 27 | 1913-1919 | |
| 45 | Doyle Walton | 27 | 1916-1917 | |
| 54 | Rory Mullins | 26 | 1967-1968 | |
| 54 | Jason Spencer | 26 | 1911-1912 | |
| 56 | Mark Davenport | 25 | 1913-1913 | |
| 56 | Justin Finley | 25 | 1948-1949 | |
| 56 | Paul Latham | 25 | 1982-1987 | |
| 56 | Robinson Moreno | 25 | 1913-1914 | |
| 56 | Ira Tindall# | 25 | 1977-1987 | |
| 61 | Luis Castro# | 24 | 1986-1986 | |
| 61 | Richard Hebert | 24 | 1972-1983 | |
| 61 | Jorge Mendoza# | 24 | 1982-1989 | |
| 61 | Ray Moran | 24 | 1957-1957 | |
| 61 | Ron Williams | 24 | 1911-1911 | |
| 66 | Theodor Frenkiel | 23 | 1943-1944 | |
| 66 | Jorge Marín# | 23 | 1979-1985 | |
| 66 | Yuki Matsushita | 23 | 1957-1961 | |
| 66 | Jesús Mercado | 23 | 1911-1914 | |
| 66 | Brad O'Cawley | 23 | 1966-1967 | |
| 66 | Gilberto Rodríguez | 23 | 1972-1974 | |
| 66 | Bernie Rowe | 23 | 1972-1974 | |
| 66 | Curt Wilkerson | 23 | 1936-1946 | |
| 66 | Stephen Willis | 23 | 1914-1914 | |
| 75 | Connor Cochran | 22 | 1962-1963 | |
| 75 | Sean Descamps | 22 | 1948-1952 | |
| 75 | Auno Lehtinen | 22 | 1975-1978 | |
| 75 | César López | 22 | 1946-1948 | |
| 75 | Blake Moore | 22 | 1970-1972 | |
| 75 | Pedro Reyes | 22 | 1975-1975 | |
| 75 | Luis Velásquez | 22 | 1915-1921 | |
| 75 | Tony Washington | 22 | 1937-1939 | |
| 75 | Sergio Zaragoza | 22 | 1963-1970 | |
| 84 | Miguel Ávila | 21 | 1913-1914 | |
| 84 | Luigino Carnazza | 21 | 1948-1952 | |
| 84 | Alberto Cervantes# | 21 | 1990-1991 | |
| 84 | Emílio García | 21 | 1923-1928 | |
| 84 | J.R. Lewis | 21 | 1949-1955 | |
| 84 | Héctor López | 21 | 1934-1935 | |
| 84 | Quintino Moroni | 21 | 1963-1965 | |
| 84 | Nick Richards | 21 | 1971-1975 | |
| 84 | Nasih Sariyah | 21 | 1973-1977 | |
| 93 | Joaquín Arteaga | 20 | 1940-1942 | |
| 93 | Mark Collins | 20 | 1957-1957 | |
| 93 | Phil Farr | 20 | 1945-1948 | |
| 93 | Larry Fleming | 20 | 1980-1988 | |
| 93 | Alfonso González | 20 | 1923-1923 | |
| 93 | Bill Hales | 20 | 1914-1916 | |
| 93 | Ralph Stoddart | 20 | 1945-1949 | |
| 93 | Tokuma Sugimoto | 20 | 1920-1921 |
